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| http://dx.doi.org/10.1007/s12288-022-01614-1 | DOI Listing |
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Diabetes is a multifactorial global health disorder marked by unusually high plasma glucose levels, which can lead to serious consequences including diabetic neuropathy, kidney damage, retinopathy, and cardiovascular disease. One effective therapy approach for reducing hyperglycemia associated with type 2 diabetes is to target α-glucosidase, enzymes that catalyze starch breakdown in the intestine. In the current study, two new (1, 2) and nine known (3-11) compounds were isolated from the rutaceous plant Haplophyllum tuberculatum and characterized by extensive nuclear magnetic resonance spectroscopic techniques and high-resolution electrospray ionization mass spectrometry.
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Pennsylvania State University Hershey Medical Center, 500 University Dr, Heshey, PA, USA.
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Department of Physics, Faculty of Electrical Engineering and Informatics, Technical University of Košice, Park Komenského 2, Košice 042 00, Slovakia.
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Department of Neurology, St. Vincent's University Hospital, Elm Park, Dublin, Ireland. Electronic address:
Many forms of autoimmune encephalitis are mediated by neuronal cell-surface directed autoantibodies. The co-occurrence of four neuronal cell-surface antibodies in a single patient is exceptionally rare. We report a patient who had a severe encephalitis associated with antibodies to NMDA, Glycine, GABA and GABA receptors.
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