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Patterns of Brain Maturation in Autism and Their Molecular Associations.
JAMA Psychiatry
December 2024
Department of Child and Adolescent Psychiatry, University Hospital Goethe University, Frankfurt am Main, Germany.
Importance: In the neurotypical brain, regions develop in coordinated patterns, providing a fundamental scaffold for brain function and behavior. Whether altered patterns contribute to clinical profiles in neurodevelopmental conditions, including autism, remains unclear.
Objectives: To examine if, in autism, brain regions develop differently in relation to each other and how these differences are associated with molecular/genomic mechanisms and symptomatology.
Genome-Derived Ampullary Adenocarcinoma Classifier and Postresection Prognostication.
JAMA Surg
December 2024
Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
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- Ampullary adenocarcinoma (AA) shows clinical and genetic diversity, and a new genomic classifier may improve patient classification beyond traditional methods, but it needs validation before being widely used.
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Prenatal Cannabis Use Before and During the COVID-19 Pandemic.
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