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Identification of Transdiagnostic Childhood Externalizing Pathology Within an Electronic Medical Records Database and Application to the Analysis of Rare Copy Number Variation.
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Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Externalizing traits and behaviors are broadly defined by impairments in self-regulation and impulse control that typically begin in childhood and adolescence. Externalizing behaviors, traits, and symptoms span a range of traditional psychiatric diagnostic categories. In this study, we sought to generate an algorithm that could reliably identify transdiagnostic childhood-onset externalizing cases and controls within a university hospital electronic health record (EHR) database.
View Article and Find Full Text PDFOne-Step Epitaxy of Transition Metal Nitride Nanopillar Arrays with an Oxidation-Tunable Hyperbolic Dispersion.
ACS Appl Mater Interfaces
January 2025
Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China.
The controllable synthesis of epitaxial nanopillar arrays is fundamentally important to the development of advanced electrical and optical devices. However, this fascinating growth method has rarely been applied to the bottom-up synthesis of plasmonic nanostructure arrays (PNAs) with many broad, important, and promising applications in optical sensing, nonlinear optics, surface-enhanced spectroscopies, photothermal conversion, photochemistry, etc. Here, a one-step epitaxial approach to single-crystalline NbTiN (NbTiN) nanopillar arrays based on the layer plus island growth mode is demonstrated by strain engineering.
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Lysosomes are the major cellular organelles responsible for nutrient recycling and degradation of cellular material. Maintenance of lysosomal integrity is essential for cellular homeostasis and lysosomal membrane permeabilization (LMP) sensitizes toward cell death. Damaged lysosomes are repaired or degraded via lysophagy, during which glycans, exposed on ruptured lysosomal membranes, are recognized by galectins leading to K48- and K63-linked poly-ubiquitination (poly-Ub) of lysosomal proteins followed by recruitment of the macroautophagic/autophagic machinery and degradation.
View Article and Find Full Text PDFThe fully bio-based bilayered flame retardant treatment for paper via natural bio-materials.
Front Chem
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School of the Environment and Safety Engineering (School of the Emergency Management), Jiangsu University, Zhenjiang, China.
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View Article and Find Full Text PDFRemote Extended Reality with Markerless Motion Tracking for Sitting Posture Training.
IEEE Robot Autom Lett
November 2024
Department of Mechanical Engineering, Columbia University, New York, NY, 10027, USA.; Department of Rehabilitation and Regenerative Medicine, Columbia University, New York, NY, 10027, USA.
Dynamic postural control during sitting is essential for functional mobility and daily activities. Extended reality (XR) presents a promising solution for posture training in addressing conventional training limitations related to patient accessibility and ecological validity. We developed a remote XR rehabilitation system with markerless motion tracking for sitting posture training.
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