AI Article Synopsis
- The study introduces a new method for converting primary alcohols or aldehydes into α,β-acetylenic ketones (ynones) using metal catalysis.
- Deuterium labeling experiments support a unique reaction mechanism where alkyne hydroruthenation creates a temporary vinylruthenium complex.
- This complex then deprotonates the terminal alkyne, producing a reactive alkynylruthenium nucleophile that drives the reaction.
Article Abstract
The first metal-catalyzed oxidative alkynylations of primary alcohols or aldehydes to form α,β-acetylenic ketones (ynones) are described. Deuterium labelling studies corroborate a novel reaction mechanism in which alkyne hydroruthenation forms a transient vinylruthenium complex that deprotonates the terminal alkyne to form the active alkynylruthenium nucleophile.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213147 | PMC |
| http://dx.doi.org/10.1002/anie.202303345 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Wellbeing and the Lived Experience of Injured Workers Following Finalisation of a Workers' Compensation Claim.
J Occup Rehabil
January 2025
Faculty of Health Sciences, Curtin School of Allied Health, Curtin University, Perth, WA, Australia.
Purpose: Workers' compensation claims can negatively affect the wellbeing of injured workers. For some, these negative effects continue beyond finalisation of the workers' compensation claim. It is unclear what factors influence wellbeing following finalisation of a workers' compensation claim.
View Article and Find Full Text PDFRevision Unicompartmental Knee Arthroplasty: Worse Than a Primary, But Better Than a Revision Total Knee Arthroplasty.
J Arthroplasty
January 2025
Rush University Medical Center, 1611 W Harrison St, Chicago, IL, 60612.
Background: Revision of a unicompartmental to a total knee arthroplasty (TKA) is often compared to primary TKA with regard to its technical difficulty and complication rates. We sought to compare medical and surgical complications following revision unicompartmental knee arthroplasty (UKA) to those following primary TKA and aseptic revision TKA.
Methods: A national administrative claims database was queried for patients undergoing revision UKA between 2010 and 2019.
Ultrasonication-assisted lipase-catalyzed esterification of chlorogenic acid: A comparative study using fatty alcohol and acids in solvent and solvent-free conditions.
Ultrason Sonochem
January 2025
Department of Chemical Engineering, National Chung Hsing University, Taichung 402, Taiwan. Electronic address:
Chlorogenic acid, a well-known antioxidant, has potential applications in health care, food, and cosmetic sectors. However, its low solubility hinders its application at the industrial scale. The primary goal of the present study was to increase the lipophilic property of chlorogenic acid through esterification using an ultrasonication approach and Novozym® 435 as the catalyst.
View Article and Find Full Text PDFCase report: Rare case of laryngeal hypertrophic lichen planus.
Int J Surg Case Rep
December 2024
Institut de Cancérologie de Lorraine, 6 avenue de Bourgogne, 54519 Vandœuvre-lès-Nancy, France; CRAN, CNRS, UMR 7039, Université de Lorraine, Vandœuvre-lès-Nancy, France.
Introduction And Importance: Lichen planus is an inflammatory and chronic disease with multifactorial causes. Hypertrophic subtype of lichen planus is an extremely rare lesion when found in the larynx. This article describes the case of a man with such a lesion.
View Article and Find Full Text PDFThe discrepancy in amino acids within high-temperature Daqu: A novel metabolic marker for the quality evaluation of Daqu.
Food Chem
December 2024
State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, College of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, China. Electronic address:
Mechanical pressing in Daqu production has introduced quality-affecting variations. Up to now, clear elucidation has not yet been applied to the mechanisms behind this phenomenon, and the determinants of Daqu quality are not yet completely excavated. For this reason, the physicochemical factors, enzyme activity, metabolites, and microbial communities were compared between the mechanical Daqu (MDQ) and traditional Daqu (TDQ) in this paper.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!