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Successful Treatment of Refractory Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) Syndrome and Paradoxical Psoriasis with Secukinumab: A Case Report.
Clin Cosmet Investig Dermatol
March 2024
Department of Dermatology, The Second Hospital of Jilin University, Changchun, Jilin, 130000, People's Republic of China.
Article Synopsis
- SAPHO syndrome is a rare chronic inflammatory condition characterized by skin and bone issues, particularly affecting the joints.
- A case study details a female patient whose psoriasis and palmoplantar pustulosis worsened while being treated with adalimumab, a TNF-α inhibitor.
- When switched to secukinumab, the patient showed significant improvements in both her skin problems and joint pain, indicating secukinumab may be a better treatment option for similar cases.
Paradoxical skin lesions induced by IL-17 inhibitors in SAPHO syndrome.
J Dermatolog Treat
December 2024
Department of Rheumatology, Fangshan Hospital, Beijing University of Chinese Medicine, Beijing, China.
Treatment and monitoring of SAPHO syndrome: a systematic review.
RMD Open
December 2023
Department of Women's & Children's Health, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK
Background And Objectives: Synovitis acne pustulosis hyperostosis osteitis (SAPHO) is a rare heterogeneous disease of unknown aetiopathology. Externally validated and internationally agreed diagnostic criteria or outcomes and, as a result, prospective randomised controlled trials in SAPHO are absent. Consequently, there is no agreed treatment standard.
View Article and Find Full Text PDFParadoxical SAPHO Syndrome after Etanercept in a Patient with Psoriasis.
Indian J Dermatol
January 2022
Dermatology Department, Hospital Universitario Araba, Francisco Leandro de Viana, Vitoria, España E-mail:
We, the Editors and Publisher of , have retracted the following article:Li Luan & Chengzhi Lv (2023) Secukinumab-induced paradoxical skin lesions, but successful treatment with tofacitinib in SAPHO syndrome: a case report, , DOI: 10.1080/09546634.2023.
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