Background: An innovative instrument for laparoscopy using indocyanine green (ICG) allows easy detection of sentinel lymph nodes (SLNs) in lateral pelvic lymph nodes (LPLNs). Here, we investigated the safety and efficacy of lateral pelvic SLN biopsy (SLNB) using ICG fluorescence navigation in advanced lower rectal cancer and evaluated the sensitivity and specificity of this technique to predict the status of LPLN.
Methods: From April 1, 2017 to December 1, 2020, we conducted lateral pelvic SLNB using ICG fluorescence navigation during laparoscopic total mesorectal excision and lateral pelvic lymph node dissection (LLND) in 23 patients with advanced low rectal cancer who presented with LPLN but without LPLN enlargement. Data regarding clinical characteristics, surgical and pathological outcomes, lymph node findings, and postoperative complications were collected and analyzed.
Results: We successfully performed the surgery using fluorescence navigation. One patient underwent bilateral LLND and 22 patients underwent unilateral LLND. The lateral pelvic SLN were clearly fluorescent before dissection in 21 patients. Lateral pelvic SLN metastasis was diagnosed in 3 patients and negative in 18 patients by frozen pathological examination. Among the 21 patients in whom lateral pelvic SLN was detected, the dissected lateral pelvic non-SLNs were all negative. All dissected LPLNs were negative in two patients without fluorescent lateral pelvic SLN.
Conclusion: This study indicated that lateral pelvic SLNB using ICG fluorescence navigation shows promise as a safe and feasible procedure for advanced lower rectal cancer with good accuracy, and no false-negative cases were found. No metastasis in SLNB seemed to reflect all negative LPLN metastases, and this technique can replace preventive LLND for advanced lower rectal cancer.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00464-023-10033-w | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Total Pelvic Exenteration with Presacral Fascia and Pelvic Musculature Excision for Pelvic Recurrence of Rectal Cancer.
Ann Surg Oncol
January 2025
Division of Colorectal Surgery, Changzheng Hospital, Navy Medical University, Shanghai, China.
Background: Local relapse has not been eradicated even in the era of total mesorectum excision. Although various approaches have been attempted, R0 resection remains the only potentially curative treatment. PATIENT AND METHODS: A 45-year-old woman with a history of laparoscopic abdominoperineal resection was diagnosed with pelvic recurrence 7 months ago.
View Article and Find Full Text PDFHip-Spine Relationship in Femoroacetabular Impingement: Does Hip Arthroscopy Affect Pelvic Mobility?
Clin Orthop Relat Res
December 2024
Naval Medical Center San Diego, San Diego, CA, USA.
Background: Femoroacetabular impingement (FAI) is a well-recognized cause of hip pain in adults. The hip-spine relationship between the femur, pelvis, and lumbosacral spine has garnered recent attention in hip arthroplasty. However, the hip-spine relationship has not been well described in patients with FAI.
View Article and Find Full Text PDFGluteus medius muscle activation patterns during gait with Cerebral Palsy (CP): A hierarchical clustering analysis.
PLoS One
January 2025
Clinic for Orthopaedics, Heidelberg University Hospital, Heidelberg, Germany.
Duchenne gait, characterized by an ipsilateral trunk lean towards the affected stance limb, compensates for weak hip abductor muscles, notably the gluteus medius (GM). This study aims to investigate how electromyographic (EMG) cluster analysis of GM contributes to a better understanding of Duchenne gait in patients with cerebral palsy (CP). We analyzed retrospective gait data from 845 patients with CP and 65 typically developed individuals.
View Article and Find Full Text PDFComparison between the SGRT and the conventional setup method for patients undergoing VMAT for pelvic malignancies.
Appl Radiat Isot
January 2025
Department of Medical Physics, Medical School, University of Crete, Heraklion, Greece. Electronic address:
Purpose: Surface Guided Radiation Treatment (SGRT) is a new method of positioning and monitoring patients on the linear accelerator's couch, using visual light cameras to monitor the skin's surface. The purpose of this study was to compare the SGRT with the conventional method, based on lasers and tattoos, in terms of accuracy and time expenditure, on patients with pelvic malignancies.
Materials And Methods: A group of 34 patients were enrolled in this study, 24 males who underwent radiotherapy prostate treatment and 10 females who underwent gynecological radiation therapy.
Acetabular orientation, pelvic shape, and the evolution of hominin bipedality.
J Hum Evol
January 2025
Department of Pathology and Anatomical Sciences, University of Missouri, Columbia, MO 65212, USA.
Hominin pelvic form differs dramatically from that of other primates by having more laterally facing iliac blades, a wider sacrum, and a larger, transversely broad pelvic inlet. The orientation of the acetabulum may also differ, plausibly related to differences in load transmission during upright posture and habitual bipedal locomotion, which may, in turn, affect overall pelvic geometry. We compared acetabular orientation in humans, a phylogenetically broad sample of extant anthropoid primates, and fossil hominins including Australopithecus afarensis (A.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!