AI Article Synopsis
- The study aimed to evaluate whether placing COVID-19 patients with acute respiratory failure in an awake prone position (aPP) could improve lung ventilation uniformity as measured by electrical impedance tomography (EIT).
- The study involved 20 patients who were tested in both the supine position and aPP, measuring their oxygenation levels and EIT readings after each interval.
- Results showed that while oxygenation improved in aPP, the global inhomogeneity index of ventilation did not significantly change in either position, indicating that aPP does not reduce lung ventilation inhomogeneity in these patients.
Article Abstract
Background: The goal of this study was to determine whether an awake prone position (aPP) reduces the global inhomogeneity (GI) index of ventilation measured by electrical impedance tomography (EIT) in COVID-19 patients with acute respiratory failure (ARF).
Methods: This prospective crossover study included COVID-19 patients with COVID-19 and ARF defined by arterial oxygen tension:inspiratory oxygen fraction ( : ) of 100-300 mmHg. After baseline evaluation and 30-min EIT recording in the supine position (SP), patients were randomised into one of two sequences: SP-aPP or aPP-SP. At the end of each 2-h step, oxygenation, respiratory rate, Borg scale and 30-min EIT were recorded.
Results: 10 patients were randomised in each group. The GI index did not change in the SP-aPP group (baseline 74±20%, end of SP 78±23% and end of aPP 72±20%, p=0.85) or in the aPP-SP group (baseline 59±14%, end of aPP 59±15% and end of SP 54±13%, p=0.67). In the whole cohort, : increased from 133±44 mmHg at baseline to 183±66 mmHg in aPP (p=0.003) and decreased to 129±49 mmHg in SP (p=0.03).
Conclusion: In spontaneously breathing nonintubated COVID-19 patients with ARF, aPP was not associated with a decrease of lung ventilation inhomogeneity assessed by EIT, despite an improvement in oxygenation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922472 | PMC |
| http://dx.doi.org/10.1183/23120541.00509-2022 | DOI Listing |
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