AI Article Synopsis
- Gout is an inflammatory arthritis caused by uric acid crystal buildup in joints, leading to pain and stiffness, commonly affecting the big toe but can involve other joints as well.
- A case study of a 43-year-old man with a history of obesity, hypertension, and gout showed bilateral leg pain and inability to walk for two years, with lab tests indicating elevated inflammation markers and negative imaging results.
- A skin biopsy confirmed tophaceous gout, and treatment effectively resolved inflammation and blood abnormalities without complications.
Article Abstract
Gout is the most common inflammatory arthritis which is caused by the buildup of uric acid crystals in the joints, that leads to severe pain, swelling, and stiffness. The condition typically affects the first metatarsophalangeal joint but it can impact other joints in the body. We present a case in which a 43-year-old male with a past medical history of obesity, hypertension, osteoarthritis, and gout presented with bilateral leg pain and the inability to walk for the last two years. Labs showed persistent leukocytosis, elevated ESR (erythrocyte sedimentation rate), normal uric acid levels, with physical exam findings of bilateral tender nodular leg lesions. Chest X-ray, head CT without contrast, left hip X-ray and ultrasound of left lower extremity were performed which were all negative. Biopsy of the tender skin nodules confirmed the diagnosis of tophaceous gout. Acute and prophylactic treatment of tophaceous gout resulted in resolved inflammation and leukocytosis without any complications.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10042487 | PMC |
| http://dx.doi.org/10.7759/cureus.36707 | DOI Listing |
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