Case Report: Simultaneously Induced Neutropenia and Hemolysis After a Single Metamizole Dose.

Drugs R D

Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology, Rheumatology and Infectious Diseases, University Medical Center Regensburg, Regensburg, Germany.

Published: June 2023

Background And Objective: Metamizole is a non-opioid ampyrone sulfonate compound with potent analgesic, antipyretic, and spasmolytic effects. Agranulocytosis is a rare life-threatening complication of metamizole.

Case: Here, we present the case of a 62-year-old patient who developed agranulocytosis as well as hemolysis after a single administration of metamizole.

Conclusion: This case illustrates the inherent allergic potential of metamizole and its effects on different hematopoietic cell types.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293139PMC
http://dx.doi.org/10.1007/s40268-023-00415-9DOI Listing

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