Background: Angiomyofibroblastoma (AMFB) is an uncommon disease with few literature reports, leading to the poor understanding of its diagnosis, treatment, and postoperative follow-up plans among gynecologists.
Objective: To study the clinical and pathological features of vulvar AMFB and discuss its treatment and prognosis.
Case Summary: The 3 cases were characterized by a gradually increasing painless mass in the vulva. Preoperative diagnosis was difficult and mainly depended on ultrasonic examination. Immunohistochemistry confirmed clear boundaries of AMFB. This condition could be completely cured by surgery, and the prognosis was good.
Conclusion: The vulvar AMFB is a rare tumor that is frequently misdiagnosed before surgery. Ultrasound is preferred in auxiliary diagnosis, and surgery remains the best treatment, and long-term follow-up is necessary to avoid recurrence or other complications.
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http://dx.doi.org/10.2147/IJWH.S403121 | DOI Listing |
Medicina (Kaunas)
October 2024
Institute of Medical Science, Gyeongsang National University, Jinju 52727, Republic of Korea.
Case Rep Womens Health
June 2024
Department of Obstetrics and Gynecology, Oncology and High-Risk Pregnancies, Maternity Hospital Souissi, Ibn Sina Teaching Hospital, University Mohammed V, 12000 Rabat, Morocco.
Angiomyofibroblastoma (AMFB) represents a rare, benign mesenchymal tumor with a predilection for the vulvovaginal region. It is usually diagnosed in middle-aged women. Histopathology and immunohistochemical study remain the key to diagnosis.
View Article and Find Full Text PDFInt J Womens Health
March 2023
Department of Ultrasound Medicine, Affiliated Hospital of Jiangnan University, Wuxi City, Jiangsu Province, People's Republic of China.
Background: Angiomyofibroblastoma (AMFB) is an uncommon disease with few literature reports, leading to the poor understanding of its diagnosis, treatment, and postoperative follow-up plans among gynecologists.
Objective: To study the clinical and pathological features of vulvar AMFB and discuss its treatment and prognosis.
Case Summary: The 3 cases were characterized by a gradually increasing painless mass in the vulva.
Cureus
September 2022
Pathology, Liaquat National Hospital and Medical College, Karachi, PAK.
Introduction Mesenchymal tumors of the lower female genital tract (FGT) are a miscellaneous group of tumors that include aggressive angiomyxoma (AAM), angiomyofibroblastoma (AMFB), cellular angiofibroma (CAF), and related entities. Histologically, these tumors are composed of stromal cells admixed with vessels, with some minor histological differences. An accurate diagnosis of these tumors is important owing to the differences in the outcome.
View Article and Find Full Text PDFGynecol Oncol Rep
May 2021
Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia.
Mesenchymal tumours of the vulva are rare and consist of two types, difficult to distinguish but with different prognoses. Angiomyofibroblastoma (AMFB) is a benign tumour, whereas Aggressive Angiomyxoma (AA) is an infiltrating tumour. We describe a 22-year-old nulliparous patient with a vulvar mass sized 19 cm in diameter.
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