Tetrabromobisphenol A (TBBPA) is a known endocrine disruptor employed in a range of consumer products and has been predominantly found in different environments through industrial processes and in human samples. In this review, we aimed to summarize published scientific evidence on human biomonitoring, toxic effects and mode of action of TBBPA in humans. Interestingly, an overview of various pretreatment methods, emerging detection methods, and treatment methods was elucidated. Studies on exposure routes in humans, a combination of detection methods, adsorbent-based treatments and degradation of TBBPA are in the preliminary phase and have several limitations. Therefore, in-depth studies on these subjects should be considered to enhance the accurate body load of non-invasive matrix, external exposure levels, optimal design of combined detection techniques, and degrading technology of TBBPA. Overall, this review will improve the scientific comprehension of TBBPA in humans as well as the environment, and the breakthrough for treating waste products containing TBBPA.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054480PMC
http://dx.doi.org/10.3390/molecules28062505DOI Listing

Publication Analysis

Top Keywords

human biomonitoring
8
tbbpa humans
8
detection methods
8
tbbpa
6
review tetrabromobisphenol
4
tetrabromobisphenol human
4
biomonitoring toxicity
4
detection
4
toxicity detection
4
detection treatment
4

Similar Publications

A near-infrared multifunctional fluorescent bio-probe with large stokes shift and high quantum yield for effective determination of heavy metal lead and pesticide glyphosate in vitro and vivo.

J Hazard Mater

December 2024

Department of Chemistry, College of Arts and Sciences, Northeast Agricultural University, Harbin 150030, PR China; Key Laboratory of Agricultural Functional Molecule Design and Utilization of Heilongjiang Province, Northeast Agricultural University, Harbin 150030, China. Electronic address:

Heavy metal contamination and pesticide residues pose significant threats to human health and ecosystems. Despite its broad applications, fluorescence imaging technology often struggles in complex ecological and biological environments due to disadvantages of background autofluorescence and low quantum yield. This study introduced a near-infrared (NIR) multifunctional "off-on-off" isophorone-based fluorescent bio-probe, DHB, characterized by a high fluorescence quantum yield (10.

View Article and Find Full Text PDF

Microbial fuel cells to monitor natural attenuation around groundwater plumes.

Environ Sci Pollut Res Int

January 2025

School of Natural and Built Environment, Queen's University Belfast, Belfast, Northern Ireland, BT7 1NN, UK.

This research presents a straightforward and economically efficient design for a microbial fuel cell (MFC) that can be conveniently integrated into a borehole to monitor natural attenuation in groundwater. The design employs conventional, transparent, and reusable PVC bailers with graphite tape and granular activated carbon to create high surface area electrodes. These electrodes are connected across redox environments in nested boreholes through a wire and variable resistor setup.

View Article and Find Full Text PDF

An exchangeable SIM probe for monitoring organellar dynamics of necrosis cells and intracellular water heterogeneity in kidney repair.

Proc Natl Acad Sci U S A

January 2025

Institute of Optical Materials and Chemical Biology, Guangxi Key Laboratory of Electrochemical Energy Materials, School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, Guangxi, People's Republic of China.

Monitoring subcellular organelle dynamics in real time and precisely assessing membrane heterogeneity in living cells are very important for studying fundamental biological mechanisms and gaining a comprehensive understanding of cellular processes. However, there remains a shortage of effective tools for these purposes. Herein, we propose a strategy to develop the exchangeable water-sensing probeAPBD for time-lapse imaging of dynamics in cellular membrane-bound organelle morphology with structured illumination microscopy at the nanoscale.

View Article and Find Full Text PDF

Portable sensor technologies are indispensable in personalized healthcare and environmental monitoring as they enable the continuous tracking of key analytes. Human sweat contains valuable physiological information, and previously developed noninvasive sweat-based sensors have effectively monitored single or multiple biomarkers. By successfully detecting biochemicals in sweat, portable sensors could also significantly broaden their application scope, encompassing non-biological fluids commonly encountered in daily life, such as mineral water.

View Article and Find Full Text PDF

Enalomics: A Mass Spectrometry-Based Approach for Profiling, Identifying, and Semiquantifying Enals in Biological Samples.

Anal Chem

January 2025

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, P. R. China.

Human cells generate a bulk of aldehydes during lipid peroxidation (LPO), influencing critical cellular processes, such as oxidative stress, protein modification, and DNA damage. Enals, highly reactive α,β-unsaturated aldehydic metabolites, are implicated in various human pathologies, especially neurodegenerative disorders, cancer, and cardiovascular diseases. Despite their importance, endogenous enals remain poorly characterized, primarily due to their instability and low abundance.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!