AI Article Synopsis

  • Bacterial infections are becoming a serious issue due to rising antibiotic resistance, prompting urgent efforts to develop new treatments or enhance existing ones.
  • Graphene decorated with silver nanoparticles (Gr-Ag) shows strong potential as an antibacterial agent, exhibiting inhibitory effects against tested bacterial strains.
  • A HEPA filter modified with Gr-Ag demonstrated enhanced bactericidal properties, particularly against Gram-negative bacteria, and effectively reduced the bacteria's ability to form colonies, suggesting a significant advancement in antibacterial technology.

Article Abstract

Bacterial infections are a major concern as antibiotic resistance poses a great threat, therefore leading to a race against time into finding new drugs or improving the existing resources. Nanomaterials with high surface area and bactericidal properties are the most promising ones that help combating microbial infections. In our case, graphene decorated with silver nanoparticles Gr-Ag (5 wt% Ag) exhibited inhibitory capacity against and . The newly formed hybrid material was next incubated with high-efficiency particulate air (HEPA) filter, to obtain one with bactericidal properties. The modified filter had greater inhibitory action against the tested strains, compared to the control, and the effect was better against the Gram-negative model. Even if the bacteria remained attached to the filters, their colony forming unit capacity was affected by the Gr-Ag (5 wt% Ag) hybrid material, when they were subsequently re-cultured on fresh agar media. Therefore, the HEPA filter modified with Gr-Ag (5 wt% Ag) has high antibacterial properties that may substantially improve the existing technology.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059912PMC
http://dx.doi.org/10.3390/microorganisms11030745DOI Listing

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