In this work, femtosecond laser pulses at high repetition rates were used to fabricate unique microstructures on the surface of Ti6Al4V. We investigated the influence of pulse overlap and laser repetition rates on structure formation. Laser texturing with a high degree of overlap resulted in melting of the material, leading to the formation of specific microstructures that can be used as cavities for drug delivery. The reason for melt formation is attributed to local heat accumulation at high repetition rates. Such structures can be fabricated on materials with low thermal conductivity, which prevent heat dissipation into the bulk of the material. The heat accumulation effect has also been demonstrated on steel, which also has low thermal conductivity.
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http://dx.doi.org/10.3390/ma16062498 | DOI Listing |
Eur J Prev Cardiol
January 2025
Department of Internal Medicine II, Division of Cardiology, Medical University of Vienna, Vienna, Austria.
Aims: We aimed to establish one-minute sit-to-stand test (1-min STST) cut-off values that align with the guideline-recommended six-minute walk test (6MWT) thresholds (165m and 440m) for one-year mortality risk stratification in pulmonary hypertension (PH) patients. Furthermore, we aimed to compare clinical characteristics and long-term mortality among patients stratified by these proposed 1-min STST cut-offs.
Methods: All patients performed the 1-min STST and 6MWT.
Nat Commun
January 2025
School of Mathematics and Physics, Queen's University Belfast, Belfast, UK.
Laser-plasma acceleration of protons offers a compact, ultra-fast alternative to conventional acceleration techniques, and is being widely pursued for potential applications in medicine, industry and fundamental science. Creating a stable, collimated beam of protons at high repetition rates presents a key challenge. Here, we demonstrate the generation of multi-MeV proton beams from a fast-replenishing ambient-temperature liquid sheet.
View Article and Find Full Text PDFEur Urol Open Sci
January 2025
Unidad NRBQ-Infecciosas, Sección de Infecciosas, Unidad de Aislamiento de Alto Nivel, Hospital Central de la Defensa Gómez Ulla, Madrid, Spain.
Background And Objective: Complicated urinary tract infections (cUTIs) are serious, potentially life-threatening infections that occur in patients with an increased disease progression risk. Antimicrobial resistance represents an important health issue worldwide, contributing to relapses, which can generate further resistances. It is necessary to clarify the role of microbiological eradication as an additional objective in the management of cUTIs.
View Article and Find Full Text PDFScand J Med Sci Sports
January 2025
Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark.
While acute exercise affects sarcoplasmic reticulum (SR) function, the impact of resistance training remains unclear. The purpose of the present study was to investigate SR Ca handling plasticity in response to moderate- and high-volume strength training in elite rowers. Twenty elite male (n = 12) and female (n = 8) rowers performed three weekly strength training sessions for 8 weeks and were randomly allocated to either perform 3 sets (3-SET) or progressive increase from 5 to 10 sets (10-SET) of 10 repetitions during the training period.
View Article and Find Full Text PDFClin Nutr ESPEN
January 2025
School of Human Nutrition, McGill University, 21111 Lakeshore Rd, Sainte-Anne-de-Bellevue, QC, H9X 3V9, Canada; Department of Anesthesia, McGill University, 1001 Decarie Blvd, Montreal, QC, H4A 3J1, Canada; Department of Surgery, McGill University, 1001 Decarie Blvd, Montreal, QC, H4A 3J1, Canada. Electronic address:
Background And Aims: Current prehabilitation programs are often limited by poor recruitment and attrition rates. Remote delivery of prehabilitation may reduce barriers to participation and maximize program retention. We aimed to assess the feasibility (uptake, retention, fidelity), preliminary effectiveness, and acceptability of delivering a technology-supported prehabilitation program remotely to oncologic surgical candidates.
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