A PHP Error was encountered

Severity: Warning

Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests

Filename: helpers/my_audit_helper.php

Line Number: 176

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 1034
Function: getPubMedXML

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3152
Function: GetPubMedArticleOutput_2016

File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

The Role of Citicoline and Coenzyme Q10 in Retinal Pathology. | LitMetric

The Role of Citicoline and Coenzyme Q10 in Retinal Pathology.

Int J Mol Sci

Instituto de Investigaciones Oftalmológicas Ramón Castroviejo, Grupo UCM 920105, IdISSC, Universidad Complutense de Madrid, 28040 Madrid, Spain.

Published: March 2023

AI Article Synopsis

  • Ocular neurodegenerative diseases like glaucoma, diabetic retinopathy, and age-related macular degeneration are leading causes of blindness among working-age and elderly individuals in developed nations.
  • Many existing treatments for these conditions do not effectively halt or slow disease progression, highlighting the need for new therapies.
  • Citicoline and coenzyme Q10, known for their neuroprotective, antioxidant, and anti-inflammatory effects, show potential in improving management of these retinal diseases based on recent studies over the last decade.

Article Abstract

Ocular neurodegenerative diseases such as glaucoma, diabetic retinopathy, and age-related macular degeneration are common retinal diseases responsible for most of the blindness causes in the working-age and elderly populations in developed countries. Many of the current treatments used in these pathologies fail to stop or slow the progression of the disease. Therefore, other types of treatments with neuroprotective characteristics may be necessary to allow a more satisfactory management of the disease. Citicoline and coenzyme Q10 are molecules that have neuroprotective, antioxidant, and anti-inflammatory properties, and their use could have a beneficial effect in ocular neurodegenerative pathologies. This review provides a compilation, mainly from the last 10 years, of the main studies that have been published on the use of these drugs in these neurodegenerative diseases of the retina, analyzing the usefulness of these drugs in these pathologies.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049438PMC
http://dx.doi.org/10.3390/ijms24065072DOI Listing

Publication Analysis

Top Keywords

citicoline coenzyme
8
coenzyme q10
8
ocular neurodegenerative
8
neurodegenerative diseases
8
role citicoline
4
q10 retinal
4
retinal pathology
4
pathology ocular
4
diseases glaucoma
4
glaucoma diabetic
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!