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Complex kinship testing using the MGIEasy Pa-SNPs genotyping kit.
Int J Legal Med
December 2024
Bioinformatics center of AMMS, Beijing, P. R. China.
Disaster victim identification and criminal investigations have intensified the demand of complex kinship testing. Compared to close relatives, distant relatives share fewer identical-by-descent genetic segments; therefore, more genetic markers are required to improve the system effectiveness. Driven by the progress of next-generation sequencing, several commercial or in-house panels, including a large number of genetic markers, have been developed and applied in forensic caseworks.
View Article and Find Full Text PDFFinding non-fluorinated alternatives to fluorinated gases used as refrigerants.
Environ Sci Process Impacts
November 2024
Institute of Biogeochemistry and Pollutant Dynamics, ETH Zürich, 8092 Zürich, Switzerland.
Hydrofluorocarbons (HFCs) and so-called hydrofluoroolefins (HFOs) are used as refrigerants in air conditioning, refrigeration, chillers, heat pumps and devices for dehumidification and drying. However, many HFCs, including R-134a and R-125, have a high global warming potential and some of the HFCs and HFOs degrade atmospherically and form trifluoroacetic acid (TFA) as a persistent degradation product. Rising levels of TFA around the globe reveal an urgent need to replace fluorinated refrigerants with non-fluorinated working fluids to avoid direct emissions due to leakage, incorrect loading or removal.
View Article and Find Full Text PDFStrategizing the removal of barriers to community pharmacist's business management capabilities.
Curr Pharm Teach Learn
December 2024
College of Medicine and Dentistry, James Cook University, Townsville, Queensland 4811, Australia. Electronic address:
The community pharmacist may be challenged by their dual role of being both a health care provider and practice manager. This commentary proposes strategies to address the barriers to the management role of the community pharmacist in practice as perceived by stakeholders: pharmacist owners, pharmacist managers, pharmacists, and pharmacy students. Whilst some community pharmacist owners may believe managerial skills are not required for the profession, all stakeholders for the most part agree on the barriers to the management role of the community pharmacist in practice and the strategies to address these barriers.
View Article and Find Full Text PDFPurpose: This study was performed to assess the risk factors for artificial urinary sphincter (AUS) explantation in a large multicenter cohort.
Methods: We retrospectively reviewed the medical records for all 1,233 implantations of the AMS-800 AUS device in male nonneurological patients from 2005 to 2020 across 13 French centers. Patients with neurological conditions were excluded from the study.
The discovery of a ten-generation m.C1494T pedigree in the east of England with probable links to King Richard III.
Eur J Med Genet
August 2024
22 Parkside Drive, Exmouth, Devon, EX8 4LB, UK. Electronic address:
This paper reports the discovery of a m.C1494T pedigree in the east of England made during a search for matrilineal relations of King Richard III. The mitochondrial DNA variant m.
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