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eradication for primary prevention of gastric cancer: progresses and challenges.
J Natl Cancer Cent
December 2024
State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, Department of Cancer Epidemiology, Peking University Cancer Hospital & Institute, Beijing, China.
Gastric cancer remains a significant global health challenge, causing a substantial number of cancer-related deaths, particularly in China. While the exact causes of gastric cancer are still being investigated, () infection has been identified as the primary risk factor, which triggers chronic inflammation and a multistage progression of gastric lesions that may lead to carcinogenesis over a long latency time. Since the 1990s, numerous efforts have focused on assessing the effectiveness of eradication in preventing new cases of gastric cancer among both the general population and patients who have undergone early-stage cancer treatment.
View Article and Find Full Text PDFEvolving Perspectives on Immune Repertoire Profiling: Challenges and Opportunities in the Era of Long-Read Sequencing.
Clin Chem
December 2024
Ramaciotti Centre for Genomics, School of Biotechnology and Biomolecular Sciences, Faculty of Science, UNSW Sydney, Kensington, Australia.
A snapshot of cancer in Chile II: an update on research, strategies and analytical frameworks for equity, innovation and national development.
Biol Res
December 2024
Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Alameda 340, 8331150, Santiago, Chile.
Introduction: Chile has achieved developed nation status and boasts a life expectancy of 81 + years; however, the healthcare and research systems are unprepared for the social and economic burden of cancer. One decade ago, the authors put forward a comprehensive analysis of cancer infrastructure, together with a series of suggestions on research orientated political policy.
Objectives: Provide an update and comment on policy, infrastructure, gender equality, stakeholder participation and new challenges in national oncology.
Comment on: Toward an optimal contraception dosing strategy.
PLoS Comput Biol
December 2024
Department of Health Sciences, University of Leicester and University Hospitals of Leicester, Leicester, United Kingdom.
The optimal contraception dosing strategy proposed by Gavina et al. recently is a commendable attempt to model a complex physiological process with potenial to apply to real-life data. However, there is a need to take into account the real challenges that arise when moving from the theory to its practical application, and it is important that lessons learnt from clinical studies be taken into consideration in any theoretical modelling.
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