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Sex Differences in Late-life Cognition: A Psychometric Network Analysis of Well-functioning Older Adults.
Am J Geriatr Psychiatry
December 2024
Department of Gerontology, Faculty of Social Welfare & Health Sciences, University of Haifa, 199 Aba Khoushy Ave, Haifa, 3498838, Israel. Electronic address:
Objective: Unidentified sex differences in old-age cognition may emerge in psychometric networks, which look beyond mean scores into the unique cognitive structure of males and females. Accordingly, this study aims to examine cognition in well-functioning older males and females with psychometric network analysis.
Methods: The current cohort (N = 2,802) of community-dwelling adults (≥65 years) was derived from the Advanced Cognitive Training for Independent and Vital Elderly study.
Evaluation of mid vs distal left anterior descending artery measures in coronary physiology assessment.
Cardiovasc Revasc Med
December 2024
Department of Internal Medicine and Division of Cardiology, Baylor Scott and White, Temple, TX, United States of America. Electronic address:
Background: Angina with no obstructive coronary artery disease (ANOCA) occurs in approximately 40 % of patients who undergo diagnostic coronary angiography for symptoms of angina. Coronary physiology assessment (CPA) is a guideline proven method to assess and diagnose these patients for an effective treatment strategy. There is currently no data regarding optimal wire or sensor position for CPA using bolus coronary thermodilution.
View Article and Find Full Text PDFA review of RNA nanoparticles for drug/gene/protein delivery in advanced therapies: Current state and future prospects.
Int J Biol Macromol
January 2025
Australasian Nanoscience and Nanotechnology Initiative (ANNI), Monash University LPO, Clayton, VIC 3168, Australia.
Nanotechnology involves the utilization of materials with exceptional properties at the nanoscale. Over the past few years, nanotechnologies have demonstrated significant potential in improving human health, particularly in medical treatments. The self-assembly characteristic of RNA is a highly effective method for designing and constructing nanostructures using a combination of biological, chemical, and physical techniques from different fields.
View Article and Find Full Text PDFTo image or not to image: Use of imaging mass spectrometry in biomedical lipidomics.
Prog Lipid Res
January 2025
Lipids in Human Pathology, Institut d'Investigació Sanitària Illes Balears (IdISBa) - Health Research Institute of the Balearic Islands, Ctra. Valldemossa 79, Module G, Floor -1, E-07120 Palma, Balearic Islands, Spain; Research Unit, University Hospital Son Espases, Ctra Valldemossa 79, E-07120 Palma, Balearic Islands, Spain. Electronic address:
Lipid imaging mass spectrometry (LIMS) allows for establishing the bidimensional distribution of lipid species within a tissue section. One of the main advantages is the generation of spatial information on lipid species distribution at a spatial (lateral) resolution bordering on single-cell resolution with no need to isolate cells. Thus, LIMS images demonstrate, with a level of detail never described before, that lipid profiles are highly sensitive to cell type and pathophysiological state.
View Article and Find Full Text PDFA systematic review for non-targeted analysis of per- and polyfluoroalkyl substances (PFAS).
Sci Total Environ
January 2025
Chemistry Matters, Calgary, Canada; Mount Royal University, Calgary, Canada.
This review follows the PRISMA guidelines to provide a systematic review of 115 peer reviewed articles that used non-targeted analysis (NTA) methods to detect per- and polyfluoroalkylated substances (PFAS). This literature highlights the significant positive impact of NTA in understanding PFAS in the environment. Within the literature a geographical bias exists, with most NTA studies (∼60 %) conducted in the United States and China.
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