COVID-19 is one of the dangerous viruses that cause death if the patient doesn't identify it in the early stages. Firstly, this virus is identified in China, Wuhan city. This virus spreads very fast compared with other viruses. Many tests are there for detecting this virus, and also side effects may find while testing this disease. Corona-virus tests are now rare; there are restricted COVID-19 testing units and they can't be made quickly enough, causing alarm. Thus, we want to depend on other determination measures. There are three distinct sorts of COVID-19 testing systems: RTPCR, CT, and CXR. There are certain limitations to RTPCR, which is the most time-consuming technique, and CT-scan results in exposure to radiation which may cause further diseases. So, to overcome these limitations, the CXR technique emits comparatively less radiation, and the patient need not be close to the medical staff. COVID-19 detection from CXR images has been tested using a diversity of pre-trained deep-learning algorithms, with the best methods being fine-tuned to maximize detection accuracy. In this work, the model called GW-CNNDC is presented. The Lung Radiography pictures are portioned utilizing the Enhanced CNN model, deployed with RESNET-50 Architecture with an image size of 255*255 pixels. Afterward, the Gradient Weighted model is applied, which shows the specific separation regardless of whether the individual is impacted by Covid-19 affected area. This framework can perform twofold class assignments with exactness and accuracy, precision, recall, F1-score, and Loss value, and the model turns out proficiently for huge datasets with less measure of time.
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http://dx.doi.org/10.1016/j.measen.2023.100735 | DOI Listing |
SSM Popul Health
March 2025
Dalla Lana School of Public Health, University of Toronto, Health Sciences Building, 155 College Street, 6th Floor, Toronto, Ontario, M5T 3M7, Canada.
Background: Multimorbidity, the co-occurrence of two or more chronic conditions, is associated with the social determinants of health. Using comprehensive linked population-representative data, we sought to understand the combined effect of multiple social determinants on multimorbidity incidence in Ontario, Canada.
Methods: Ontario respondents aged 20-55 in 2001-2011 cycles of the Canadian Community Health Survey were linked to administrative health data ascertain multimorbidity status until 2022.
J Cardiol
January 2025
Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan.
Background: Alcohol septal ablation (ASA) is used to treat drug-refractory hypertrophic obstructive cardiomyopathy (HOCM). Intraprocedural echocardiography is essential for identifying the septal area perfused by each septal branch; however, its role in determining the procedural endpoint of ASA remains unclear. This retrospective study aimed to evaluate the impact of intraprocedural echocardiographic findings on clinical outcomes and left ventricular pressure gradient (LVPG) after ASA.
View Article and Find Full Text PDFInvest Radiol
January 2025
From the Departments of Radiology (J.F.H., S.Y.C., J.-P.G., J.S., P.N., S.B.R., T.M.G.), Biomedical Engineering (S.B.R., T.M.G.), Medical Physics (S.Y.C., S.B.R., T.M.G.), Medicine (S.B.R.), and Emergency Medicine (S.B.R.), University of Wisconsin-Madison, WI; and Department of Diagnostic and Interventional Radiology (J.F.H., J.-P.G.), University Hospital Würzburg, Würzburg, Germany.
Rationale And Objectives: Pulmonary magnetic resonance angiography (MRA) is an imaging method with proven utility for the exclusion of pulmonary embolism and avoids the need for ionizing radiation and iodinated contrast agents. High-relaxivity gadolinium-based contrast agents (GBCAs), such as gadopiclenol, can be used to reduce the required gadolinium dose for pulmonary MRA. The aim of this study was to compare the contrast enhancement performance of gadopiclenol with an established gadobenate dimeglumine-enhanced pulmonary MRA protocol.
View Article and Find Full Text PDFBiotechnol Prog
January 2025
Automation, Digital and Learning Solutions, Cytiva, Karlsruhe, Germany.
Mechanistic modeling of chromatographic steps is an effective tool in biopharma process development that enhances process understanding and accelerates optimization efforts and subsequent risk assessment. A relatively new model for ion exchange chromatography is the colloidal particle adsorption (CPA) formalism, which promises improved separation of material and molecule-specific parameters. This case study demonstrates a straightforward CPA modeling workflow to describe an ion exchange chromatography polishing step of a knobs-into-holes construct bispecific antibody molecule.
View Article and Find Full Text PDFAdv Mater
January 2025
Department of Mechanical & Industrial Engineering, University of Toronto, 5 King's College Road, Toronto, M5S 3G8, Canada.
Nanoarchitected materials are at the frontier of metamaterial design and have set the benchmark for mechanical performance in several contemporary applications. However, traditional nanoarchitected designs with conventional topologies exhibit poor stress distributions and induce premature nodal failure. Here, using multi-objective Bayesian optimization and two-photon polymerization, optimized carbon nanolattices with an exceptional specific strength of 2.
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