AI Article Synopsis
- Astaxanthin (ASX) is a carotenoid known for its strong antioxidant properties and potential health benefits in preventing diseases like cancer and diabetes.
- Its medical use is limited by issues such as poor water solubility and chemical instability.
- Recent advancements in nano-based drug delivery systems, like nanoparticles and liposomes, show promise for enhancing Astaxanthin's stability, efficacy, and targeted delivery in clinical applications.
Article Abstract
Astaxanthin (ASX) is a kind of carotenoid widely distributed in nature, which has been shown to extremely strong antioxidative effects and significant preventive and therapeutic effects on cancer, diabetes, cardiovascular disease, etc. However, its application in the medical field is greatly limited due to its poor water solubility, unstable chemical properties and other shortcomings. In recent years, the nano-based drug delivery systems such as nanoparticles, liposomes, nanoemulsions, nanodispersions, and polymer micelles, have been used as Astaxanthin delivery carriers with great potential for clinical applications, which have been proved that they can enhance the stability and efficacy of Astaxanthin and achieve targeted delivery of Astaxanthin. Herein, based on the pharmacological effects of Astaxanthin, we reviewed the characteristics of various drug delivery carriers, which is of great significance for improving the bioavailability of Astaxanthin.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034004 | PMC |
| http://dx.doi.org/10.3389/fphar.2023.1102888 | DOI Listing |
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