A syphilitic aortitis is a late cardiovascular lesion of tertiary syphilis that has become exceptionally rare in the antibiotic era but not eradicated completely. Syphilitic aortitis of ascending aorta complicates in ascending aortic aneurysm formation and aortic valve regurgitation, both requiring surgical treatment. After surgery, lifelong surveillance of the remainder of the aorta is recommended because of a priori supposed high incidence of delayed involvement of noninvolved aortic segments. A 3-year follow-up result of surgery of syphilitic ascending aortic aneurysm with aortic valve regurgitation in condition of active ongoing syphilitic aortitis and valvulitis is described with addressing the dimensions of remaining aortic segments. This case demonstrates that the dilatation of the remainder of the aorta does not occur during 3 years, at least when anti-syphilitic course of antibiotic is used just after operation without additional treatment during the follow-up period. A few reports on surgical treatment of syphilitic aneurysms of the ascending aorta are discussed.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10902664 | PMC |
http://dx.doi.org/10.5761/atcs.cr.22-00236 | DOI Listing |
Microorganisms
December 2024
Clinical Department of Dermatology, Medical University of Silesia, Marii Curie-Skłodowskiej 10, 41-800 Zabrze, Poland.
Syphilis, caused by the highly invasive pathogen , remains one of the oldest and most significant public health challenges. According to the World Health Organization (WHO), the number of new syphilis cases among adults aged 15-49 years in 2022 was estimated at approximately 8 million, with notable increases observed in Europe, the Americas, and Africa. The cellular immune response plays a critical role in combating this infection, and its insufficient activity may contribute to chronic progression of the disease.
View Article and Find Full Text PDFJ Int AIDS Soc
January 2025
Center for Disease Control and Prevention of Central Theater Command of Chinese People's Liberation Army, Beijing, China.
Introduction: In 2010, China launched the 10-year National Syphilis Prevention and Control Program to curb the spread of syphilis by integrating syphilis screening and treatment with HIV services. Herein, we aimed to evaluate changes in the prevalence of syphilis among people living with HIV (PLHIV) in China.
Methods: We conducted this systematic review and meta-analysis by searching the PubMed, Embase, Web of Science, China Biomedical Literature, China National Knowledge Infrastructure, Wanfang and CQVIP databases from inception to 1 June 2024 to obtain relevant articles.
Sci Prog
December 2024
Cardiology and Internal Medicine Department, Fundación Clínica Shaio, Bogotá, Colombia.
JACC Case Rep
November 2024
Division of Cardiology, Department of Medicine, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, USA.
Pathogens
November 2024
Department of Microbiology and Medical Laboratory Immunology, Medical University of Lodz, 92-213 Lodz, Poland.
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