Aspergillus terreus microorganism represents a promising prospective source for drug discovery since it is rich in diverse kinds of bioactive secondary metabolites. It contributed to many biotechnological applications and its metabolites are used in the synthesis of certain pharmaceuticals and food products, in addition to its useful uses in fermentation processes. There are about 346 compounds identified from marine and terrestrial-derived A. terreus from 1987 until 2022, 172 compounds of them proved a vast array of bioactivity. This review aimed to create an up-to-date comprehensive literature data of A. terreus's secondary metabolites classes supported by its different bioactivity data to be a scientific record for the next work in drug discovery.
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| http://dx.doi.org/10.1186/s40694-023-00153-2 | DOI Listing |
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Article Synopsis
- The ethyl acetate extract from the endophytic fungus Aspergillus terreus found in Artemisia arborescens L. led to the discovery of five new compounds, asperterreunolides A-E, along with a known metabolite, butyrolactone IV.
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