The In2Care EaveTube is a house modification designed to block and kill malaria mosquitoes using an electrostatic netting treated with insecticide powder. A previous study demonstrated prolonged duration of effective action of insecticide-treated electrostatic netting in a semi-field setting. As part of a cluster randomized controlled trial (CRT) of the EaveTube intervention in Côte d'Ivoire, we investigated the residual efficacy of a pyrethroid insecticide deployed in EaveTubes under village conditions of use. We also explored the scope of using existing malaria control technologies including LLINs and IRS as alternative methods to deliver insecticides in the lethal house lure. The efficacy of beta-cyfluthrin was monitored over time using the "eave tube bioassay" method. Mortality of beta-cyfluthrin exposed pyrethroid resistant Anopheles gambiae mosquitoes was > 80% after 4 months. The impact (mosquito mortality) of PVC tubes coated with pirimiphos methyl was similar to that of beta-cyfluthrin treated insert (66.8 vs. 62.8%) in release-recapture experiments in experimental huts. Efficacy was significantly lower with all the LLINs tested; however, the roof of PermaNet 3.0 induced significantly higher mosquito mortality (50.4%) compared to Olyset Plus (25.9%) and Interceptor G2 (21.6%) LLINs. The efficacy of the alternative delivery methods was short-lived with mortality decreasing below 50% within 2 months in residual activity bioassays. None of the products tested appeared superior to the powder treatments. Further research is therefore required to identify suitable insecticide delivery options in EaveTube for malaria vector control.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039065 | PMC |
| http://dx.doi.org/10.1038/s41598-023-31116-7 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Vaccination strategies to identify and reach zero-dose and under-immunized children in crisis-affected states in Sudan: a qualitative study.
Confl Health
December 2024
Health in Humanitarian Crises Centre, London School of Hygiene & Tropical Medicine, London, UK.
Background: Globally, 21 million children were un- or under-vaccinated with Diphtheria-Tetanus-Pertussis (DTP)-containing vaccines in 2023. Around 20% of zero-dose children, those who had not received any DTP doses, live in conflict-affected settings in low and middle-income countries. There is insufficient evidence on vaccination interventions to identify and reach zero-dose children in these settings.
View Article and Find Full Text PDFCellulose nanocrystals-based Pickering emulsion with enhanced foliar adhesion and pH responsiveness for intelligent delivery of pesticides.
Int J Biol Macromol
December 2024
College of Chemistry and Chemical Engineering, Xinjiang Agricultural University, Urumqi 830052, Xinjiang, PR China. Electronic address:
Pickering emulsions stabilized by functionalized natural macromolecules have emerged with promising responsiveness for pesticide encapsulation and release. This study developed Pickering emulsions using amine-modified cellulose nanocrystals (ACNCs) as stabilizers. The resultant O/W ACNCs-Pickering emulsions (ACNCs-Pickering) exhibited long-term storage stability and showed increasing emulsion stability depending on the concentration of ACNCs.
View Article and Find Full Text PDFGeneral aspects, host interaction, and application of sp. in arthropod pest and vector control.
Front Fungal Biol
November 2024
Laboratorio de Bioquímica e Fisiologia de Insetos, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
The application of microorganisms as bio-control agents against arthropod populations is a need in many countries, especially in tropical, subtropical, and neotropical endemic areas. Several arthropod species became agricultural pests of paramount economic significance, and many methods have been developed for field and urban applications to prevent their, the most common being the application of chemical insecticides. However, the indiscriminate treatment based upon those substances acted as a selective pressure for upcoming resistant phenotype populations.
View Article and Find Full Text PDFBacillus thuringiensis Cry5, Cry21, App6 and Xpp55 proteins to control Meloidogyne javanica and M. incognita.
Appl Microbiol Biotechnol
December 2024
Institute BIOTECMED/Department of Genetics, University of Valencia, Burjassot, Spain.
Article Synopsis
- The increased focus on biological pesticides for crop protection has led to studying Bacillus thuringiensis (Bt) and its toxic proteins against harmful root-knot nematodes.
- In laboratory tests, proteins Cry5, Cry21, App6, and Xpp55 showed high levels of toxicity against root-knot nematodes M. incognita and M. javanica.
- However, in field tests with cucumber and tomato plants, the effectiveness of the Bt proteins varied by plant type, suggesting that how these proteins are delivered is critical for their pest control success.
Dendritic mesoporous silica-delivered siRNAs nano insecticides to prevent Sogatella furcifera by inhibiting metabolic detoxification and reproduction.
J Nanobiotechnology
November 2024
State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu, 611130, China.
Article Synopsis
- Sogatella furcifera is a significant pest threatening rice production, requiring innovative management methods beyond traditional insecticides, which lead to resistance.
- A new approach using dendritic mesoporous silica nanoparticles (DMSNs) enhances the delivery of siRNA and a pesticide (nitenpyram) to effectively disrupt the insect's metabolic processes.
- This method improves the stability and release of siRNA, significantly lowering pest development and increasing susceptibility to nitenpyram, thereby presenting a promising strategy for sustainable rice agriculture.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!