AI Article Synopsis
- - Phototherapy uses light to activate agents that can kill cancer cells and control tumor growth through processes like hyperthermia and reactive oxygen species production.
- - Nanoparticles are effective carriers for these phototherapeutic agents, improving their delivery to tumors and enhancing their effectiveness through combination strategies.
- - Recent advances focus on boosting the immune response by integrating nanoparticle technology with phototherapy, leading to more lasting and widespread cancer-fighting effects.
Article Abstract
Phototherapy is an emerging approach for cancer treatment that is effective at controlling the growth of primary tumors. In the presence of light irradiation, photothermal and photodynamic agents that are delivered to tumor sites can induce local hyperthermia and the production of reactive oxygen species, respectively, that directly eradicate cancer cells. Nanoparticles, characterized by their small size and tunable physiochemical properties, have been widely utilized as carriers for phototherapeutic agents to improve their biocompatibility and tumor-targeted delivery. Nanocarriers can also be used to implement various codelivery strategies for further enhancing phototherapeutic efficiency. More recently, there has been considerable interest in augmenting the immunological effects of nanoparticle-based phototherapies, which can yield durable and systemic antitumor responses. This review provides an overview of recent developments in using nanoparticle technology to achieve photo-immunotherapy.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192221 | PMC |
| http://dx.doi.org/10.1002/smtd.202300252 | DOI Listing |
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