Primary tuberculosis of the cavum is a rare entity. It can occur at any age, especially between the second and ninth decade. We report the case of a 17-years-old patient with nasal obstruction and left laterocervical adenomegaly. A cervico-facial CT scan showed a suspicious looking tumor process of the nasopharynx. Histological analysis of the biopsies taken showed chronic granulomatous inflammation with necrosis and the absence of tuberculosis lesions in the usual sites, especially the lungs, led to the diagnosis of primary tuberculosis of the cavum. There was a good evolution on antituberculosis drugs. This unusual location can be a source of difficulties and delay in diagnosis, especially because of the clinical presentation, which suggests a nasopharyngeal tumour. In developing countries, where this disease remains relatively endemic, cross-sectional imaging techniques and histopathological analysis are of great interest for the management of patients.
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http://dx.doi.org/10.1016/j.annpat.2023.03.001 | DOI Listing |
Ann Pathol
November 2023
Département des sciences morphologiques et d'anatomie pathologique, faculté de médecine et des Sciences biomédicales, université de Yaoundé I, 1634 Yaoundé, Cameroun.
Primary tuberculosis of the cavum is a rare entity. It can occur at any age, especially between the second and ninth decade. We report the case of a 17-years-old patient with nasal obstruction and left laterocervical adenomegaly.
View Article and Find Full Text PDFPan Afr Med J
January 2021
Pulmonology Unit, Avicenne Military Hospital, Marrakech, Morocco.
Miliary pharyngeal tuberculosis or Isambert disease is a rare form of tuberculosis. It can be isolated or more often associated with lung damage. We report the case of a 25-year-old patient referred for deep asthenia with fever, sweating and weight loss, all associated with dysphagia and hearing loss.
View Article and Find Full Text PDFBMJ Case Rep
November 2015
Service de Maladies Infectieuses, Centre Hospitalier de la Croix-Rousse, Hospices Civils de Lyon, France.
An 85-year-old woman presented for assessment of recurring episodes of intense hemifacial pain, mimicking trigeminal neuralgia, associated with tinnitus. A necrotic tumour of the cavum with compression of the left Eustachian tube and skull-base invasion was discovered on brain MRI. Although the tumour was initially thought to be malignant, the histopathological findings on the biopsy were compatible with tuberculosis, later confirmed by the cultures.
View Article and Find Full Text PDFActa Otorrinolaringol Esp
August 2017
Servicio de Otorrinolaringología Hospital Militar de Instrucción Mohamed V, Rabat, Marruecos.
Tuberculosis is a public health problem for many countries, whether rich or poor. Extranodal ENT locations are rare, and it prevails in the cavum in the pharyngeal region. Based on a 3-year retrospective study of 5 clinical cases, the authors aim to highlight the epidemiological, clinical, radiological, therapeutic and prognostic aspects of this disease.
View Article and Find Full Text PDFJ Otolaryngol
August 2007
Service d'oto-rhino-laryngologie, CHU Hassan II, Fès, Maroc.
Nasopharyngeal tuberculosis is increasingly frequent and poses a diagnostic and therapeutic problem. Through a retrospective study spread out over 4 years, we brought back six cases of nasopharyngeal tuberculosis, including two men and four women of an average age of 41 years. The diagnosis was made, for all of our patients, after histologic study when we found typical tuberculosis lesions on biopsy specimens.
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