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Integrated multi-omics profiling reveals neutrophil extracellular traps potentiate Aortic dissection progression.
Nat Commun
December 2024
Department of Vascular Surgery, Zhongshan Hospital, Fudan University, 200032, Shanghai, China.
Adverse aortic remodeling increases the risk of aorta-related adverse events (AAEs) after thoracic endovascular aortic repair (TEVAR) and affects the overall prognosis of aortic dissection (AD). It is imperative to delve into the exploration of prognostic indicators to streamline the identification of individuals at elevated risk for postoperative AAEs, and therapeutic targets to optimize the efficacy of TEVAR for patients with AD. Here, we perform proteomic and single-cell transcriptomic analyses of peripheral blood and aortic lesions, respectively, from patients with AD and healthy subjects.
View Article and Find Full Text PDFPopliteal Artery Injury After Arthroscopic Knee Surgery: A Retrospective Multicenter Cohort Study.
Orthop Surg
December 2024
Department of Orthopaedics, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Objective: Popliteal artery injury is a rare but serious complication of arthroscopic knee surgery. The absence of comprehensive data and standardized guidelines underscores the urgent need for further investigation. This study examines the incidence, risk factors, management strategies, and long-term outcomes of popliteal artery injury in the context of arthroscopic knee procedures.
View Article and Find Full Text PDFNeed for and update on clinical trials for uncomplicated type B aortic dissection.
JVS Vasc Insights
January 2024
Academic Department of Vascular Surgery, South Bank Section, School of Cardiovascular and Metabolic Medicine and Sciences, King's College London, British Heart Foundation Centre of Research Excellence, St Thomas' Hospital, London, UK.
The mainstay of management for uncomplicated type B aortic dissection is currently optimal medical therapy, targeting blood pressure and heart rate, along with serial imaging. There is a paucity of data that informs whether early intervention with thoracic endografting in this group of patients will promote aortic remodeling and better long-term outcomes. Investigations to date, including the Investigation of Stent Grafts in Aortic Dissection (INSTEAD), INSTEAD-XL, and Acute Dissection: Stent Graft or Best Medical Therapy (ADSORB) studies, have compared thoracic endovascular aortic repair (TEVAR) with optimal medical therapy in patients with uncomplicated type B aortic dissection but have not shown a benefit for TEVAR conclusively.
View Article and Find Full Text PDFVisceral Artery Aneurysms: A 40-Year Experience from a Single Center.
Ann Vasc Surg
December 2024
Departamento de Cirugía Vascular y Endovascular, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. Electronic address:
Background: Visceral artery aneurysms (VAAs) are a relatively uncommon phenomenon, occurring all types of VAA at an incidence of 0.01% to 0.2%.
View Article and Find Full Text PDFTwenty-year results of open surgical suprarenal aortic fenestration for acute complicated type B aortic dissection.
Ann Vasc Surg
December 2024
Department of Interventional Radiology, Semmelweis University, Budapest, Hungary; Semmelweis Aortic Center, Heart and Vascular Center, Semmelweis University, Budapest, Hungary. Electronic address:
Objective: Open surgical suprarenal aortic fenestration (OSSAF) is a technique to treat complicated type B aortic dissection (cTBAD) by resecting the intimal membrane at the level of the visceral arteries. This invasive procedure is largely abandoned since the advent of thoracic endovascular aortic repair (TEVAR) as becoming the gold standard of treating cTBAD. Identifying patterns in the late history of patients who underwent OSSAF might help better understand the evolution of TBAD.
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