Cutaneous Manifestations in Hereditary Alpha Tryptasemia.

Cutis

Drs. Kranyak and Shuler are from the University of South Carolina School of Medicine, Greenville. Dr. Wine Lee is from the Departments of Dermatology and Pediatrics, Medical University of South Carolina, Charleston.

Published: January 2023

Hereditary alpha tryptasemia (HaT) is a recently identified disorder that is associated with dermatologic manifestations such as urticaria, flushing, pruritus, and atopic dermatitis (AD), as well as a broad range of other symptoms affecting multiple systems. Given the potential cutaneous manifestations and the fact that dermato-logic symptoms may be the initial presentation of HaT, awareness and recognition of this condition by dermatologists are essential for diagnosis and treatment. This review aims to summarize cutaneous presentations consistent with HaT and various conditions that share overlapping dermatologic symptoms with HaT.

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Source
http://dx.doi.org/10.12788/cutis.0682DOI Listing

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