Case: A 25-year-old man presented 18 hours after Candida albicans antigen injection into a left index finger cutaneous wart by his dermatologist. He experienced a rapid-onset inflammatory response, which was indistinguishable from gangrenous infection. Urgent incision and drainage was performed; however, no purulent collection was noted and no organism isolated. At 1-year follow-up, he made a full recovery.
Conclusion: Intralesional C. albicans antigen injection in digital cutaneous warts may cause an exaggerated immune response resulting in partial necrosis of the finger pulp. The clinical presentation may be difficult to distinguish from coexisting infection, but in some cases, observation may be an appropriate course of action.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2106/JBJS.CC.22.00748 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Identification of Antigens Recognized by Murine Intestinal IgAs by a Gel-Independent Immunoproteomic Approach.
J Proteome Res
January 2025
Departamento de Microbiología y Parasitología, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza de Ramón y Cajal s/n, 28040 Madrid, Spain.
As part of the intestinal microbiota, can elicit a humoral response in the gastrointestinal tract (GIT) that is mainly directed toward hyphal antigens. This response has been implicated in controlling the invasive form of the fungus and maintaining the yeast as an innocuous commensal. However, the specific targets of this response are still unknown.
View Article and Find Full Text PDFCRISPR technology combined with isothermal amplification methods for the diagnosis of Candida albicans infection.
Clin Chim Acta
December 2024
Department of Clinical Laboratory, the First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China; Department of Clinical Laboratory, Anhui Public Health Clinical Center, Hefei, People's Republic of China. Electronic address:
Since Candida albicans, a type of fungus, causes severe infections that pose a significant threat to human health, its rapid detection is critical in clinical antifungal therapy. Traditional fungal diagnostic approaches are largely based on the culture method. This method is time-consuming and laborious, taking about 48-72 h, and cannot identify emerging species, making it unsuitable for critically ill patients with bloodstream infections, sepsis, and so on.
View Article and Find Full Text PDFCommunity-Acquired Pneumonia in Adults: A Mono-Center Retrospective Study.
Tanaffos
January 2024
Department of Radiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Article Synopsis
- Adult community-acquired pneumonia is a major health issue, leading to hospitalizations and deaths. A study looked at adult patients hospitalized due to pneumonia during the cold seasons of 2018 and 2019, identifying various microorganisms responsible for the infections.
- Of 205 patients, 57% had identifiable microorganisms, with Influenza H1N1 2009 being the most common, followed by Tuberculosis, non-albicans Candida, and methicillin-resistant Staphylococcus Epidermidis, with pneumonia cases showing a concerning mortality trend associated with staphylococcal infections.
- The findings emphasize the need for prompt, specific treatment protocols for staphylococcal pneumonia and highlight the necessity of considering both community-acquired
In vitro and in vivo studies of selenium nanoparticles coated bacterial polysaccharide as anti-lung cancer agents.
Microb Cell Fact
December 2024
Department of Botany and Microbiology, Faculty of Science, Alexandria University, Alexandria, Egypt.
Microbial exopolysaccharides (EPSs) possess valuable biological functions and fascinating physicochemical properties. On the other hand, lung cancer is the primary contributor to global cancer-related deaths. However, health and safety concerns have prevented the identification and approval of any medications, including chemotherapeutic agents, for lung cancer treatment to date.
View Article and Find Full Text PDFEfficacy of lipid nanoparticles-based vaccine to protect against vulvovaginal candidiasis (VVC): Implications for women's reproductive health.
Life Sci
January 2025
Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraidah 51452, Saudi Arabia.
Aims: Vulvovaginal candidiasis (VVC) is a common women's health issue, with rising antifungal resistance. This study was aimed to prepare and evaluate the efficacy of a lipid nanoparticle-based vaccine in a murine model of VVC.
Materials And Methods: Dried and reconstituted vesicles containing C.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!