Carcinoma en Cuirasse.

JAMA Dermatol

Department of Dermatology, Rush University Medical Center, Chicago, Illinois.

Published: May 2023

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http://dx.doi.org/10.1001/jamadermatol.2022.5934DOI Listing

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Article Synopsis
  • Carcinoma en cuirasse is a rare skin metastasis mainly linked to breast cancer in women, showing up as various skin lesions, often long after the original cancer diagnosis.
  • Diagnosis is difficult but can be confirmed through histological examination to differentiate it from other skin issues.
  • Treatment options are not clearly established because there are few reported cases, highlighted by a case of a 30-year-old woman whose breast cancer developed into carcinoma en cuirasse within 6 months.
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Carcinoma en cuirasse is a type of cutaneous metastasis from different malignancies. En cuirasse although is a rare entity, most commonly occurs in cases of recurrent breast carcinoma after surgery or very rarely months or years after diagnosis of primary tumor. We report a rare case of neck carcinoma en cuirasse in a 47-year-old Indian female who is a known case of recurrent carcinoma left breast postmodified radical mastectomy, chemotherapy, and radiotherapy referred for fluorodeoxyglucose positron emission tomography-computed tomography following another six cycles of chemotherapy for response assessment.

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Carcinoma en cuirasse (CeC) is an uncommon presentation of metastatic cutaneous carcinoma, most often originating from breast carcinoma. We present a case study of a man in his 30s exhibiting progressive skin thickening over the left chest, alongside appetite and weight loss. On examination, the patient had painless skin induration and palpable, matted, hard, immobile and non-tender axillary, cervical and inguinal lymphadenopathy.

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Article Synopsis
  • A 63-year-old male developed a painful skin lesion on his neck and chest that did not improve with antibiotics, prompting further investigation.
  • A punch biopsy indicated the presence of poorly differentiated tumor cells, leading to suspicion of carcinoma based on both skin and radiologic findings.
  • Eventually, he was diagnosed with carcinoma en cuirasse, a type of breast cancer that has spread to the skin, and was referred to oncology for palliative chemotherapy.
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