Background And Hypothesis: Any form of coherent discourse depends on saying different things about the same entities at different times. Such recurrent references to the same entity need to predictably happen within certain temporal windows. We hypothesized that a failure of control over reference in speakers with schizophrenia (Sz) would become manifest through dynamic temporal measures.
Study Design: Conversational speech with a mean of 909.2 words (SD: 178.4) from 20 Chilean Spanish speakers with chronic Sz, 20 speakers at clinical high risk (CHR), and 20 controls were collected. Using directed speech graphs with referential noun phrases (NPs) as nodes, we studied deviances in the topology and temporal distribution of such NPs and of the entities they denote over narrative time.
Study Results: The Sz group had a larger density of NPs (number of NPs divided by total words) relative to both controls and CHR. This related to topological measures of distance between recurrent entities, which revealed that the Sz group produced more recurrences, as well as greater topological distances between them, relative to controls. A logistic regression using five topological measures showed that Sz and controls can be distinguished with 84.2% accuracy.
Conclusions: This pattern indicates a widening of the temporal window in which entities are maintained in discourse and co-referenced in it. It substantiates and extends earlier evidence for deficits in the cognitive control over linguistic reference in psychotic discourse and informs both neurocognitive models of language in Sz and machine learning-based linguistic classifiers of psychotic speech.
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http://dx.doi.org/10.1093/schbul/sbac102 | DOI Listing |
Rev Colomb Psiquiatr (Engl Ed)
December 2024
Department of Psychiatry, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Introduction: It has been shown that public stigma towards people with schizophrenia hinders their psychosocial integration. Public stigma expresses itself through lexical labels used in the print media and social networks, heightening the internalization of stigma in this population, a phenomenon known as internalised stigma or self-stigma. This paper analyses the diffusion in the mass media of two dimensions of stigma: public stigma and self-stigma.
View Article and Find Full Text PDFComprehensible communication is critical for social functioning and well-being. In psychopathology, incoherent discourse is assumed to reflect disorganized thinking, which is classically linked to psychotic disorders. However, people do not express everything that comes to mind, rendering inferences from discourse to the underlying structure of thought challenging.
View Article and Find Full Text PDFJ Psychiatry Neurosci
August 2024
From CIDCL, Escuela de Fonoaudiología, Universidad de Valparaíso, Valparaíso, Chile (Alonso-Sánchez); the Department of Translation & Language Sciences, Universitat Pompeu Fabra, Barcelona, Spain (Hinzen, He); the Intitut Català de Recerca i Estudis Avançats (ICREA), Barcelona, Spain (Hinzen); the Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, Ont. (Gati, Palaniyappan); the Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Ont. (Gati, Palaniyappan); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montréal, Que (Palaniyappan)
Background: Psychosis involves a distortion of thought content, which is partly reflected in anomalous ways in which words are semantically connected into utterances in speech. We sought to explore how these linguistic anomalies are realized through putative circuit-level abnormalities in the brain's semantic network.
Methods: Using a computational large-language model, Bidirectional Encoder Representations from Transformers (BERT), we quantified the contextual expectedness of a given word sequence (perplexity) across 180 samples obtained from descriptions of 3 pictures by patients with first-episode schizophrenia (FES) and controls matched for age, parental social status, and sex, scanned with 7 T ultra-high field functional magnetic resonance imaging (fMRI).
Schizophr Res
August 2024
Alabama Life Research Institute, The University of Alabama, Tuscaloosa, AL, United States of America.
Discourse abnormalities are a prominent feature in schizophrenia spectrum disorders, including poor lexical diversity, and have been found to differentiate patients from healthy subjects. However, discourse processing in individuals with high schizotypal personality traits is less understood and is often overshadowed by research on clinical psychotic symptoms. In the present study, we examined schizotypal traits at a non-clinical threshold and their association with lexical diversity and discourse coherence using two automated Natural Language Processing (NLP) tools - Type-Token-Ratio (TTR) measures from the Tool for the Automatic Analysis of Lexical Diversity (TAALED) and discourse coherence using sentence-level average cosign similarity with FastText to assess sentence similarity.
View Article and Find Full Text PDFEarly Interv Psychiatry
May 2024
Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.
Aim: Early interventions are well understood to improve psychosis outcomes, but their successful implementation remains limited. This article introduces a three-step roadmap for advancing the implementation of evidence-based practices to operate as a learning health system, which can be applied to early interventions for psychosis and is intended for an audience that is relatively new to systematic approaches to implementation.
Methods: The roadmap is grounded in implementation science, which specializes in methods to promote routine use of evidence-based innovations.
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