AI Article Synopsis
- The study explored the antiallergic effects of phlorotannin concentrate (PTC) derived from the brown alga Eisenia nipponica on cedar pollinosis in mice.
- PTC significantly reduced symptoms like sneezing and nasal rubbing in the mice.
- The observed effects were linked to lower levels of immunoglobulin E and specific Th2-type cytokines associated with allergic reactions (IL-4, IL-5, IL-13).
Article Abstract
The antiallergic properties of phlorotannins, algal polyphenols, have been widely reported. This study examined the soothing effect of phlorotannin concentrate (PTC) from Eisenia nipponica on cedar pollinosis in Cry j 1-stimulated mice. PTC reduced the mice's sneezing and nasal rubbing, which was attributed to decreased levels of immunoglobulin E and Th2-type cytokines [interleukin (IL)-4, IL-5, and IL-13].
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| http://dx.doi.org/10.1093/bbb/zbad032 | DOI Listing |
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