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Neuroimaging to diagnose central nervous system tumours in children. | LitMetric

AI Article Synopsis

  • Headaches, vomiting, lethargy, and seizures in healthy children can signal both benign viral illnesses and serious issues like CNS tumors, making diagnosis challenging.
  • Concerns over radiation from CT scans and sedation risks for MRIs lead to hesitation among guardians and primary care providers regarding timely imaging.
  • The HeadSmart initiative suggests obtaining brain imaging within 4 weeks of persistent symptoms for identifying CNS tumors; applying similar guidelines in Canada could help prevent delays in diagnosis.

Article Abstract

Question: Headache, vomiting, lethargy, and seizures are common symptoms in healthy children with benign viral illnesses, but they are also signs that could represent a central nervous system (CNS) tumour. Primary care providers and guardians are hesitant to expose children to radiation associated with computed tomography scans or take on risks associated with the sedation frequently needed for magnetic resonance imaging. When should primary care providers order radiologic head imaging for children with common symptoms to identify those with a CNS tumour?

Answer: Central nervous system tumours have no pathognomonic features, which often results in delays in diagnosis. Owing to the high prevalence of infratentorial tumours, children commonly present with symptoms of increased intracranial pressure, making a detailed history and a comprehensive physical examination, including ophthalmoscopy for papilledema, especially important. Magnetic resonance imaging is the criterion standard test but it may take time to access, and young children may need sedation. Hence, computed tomography may be a preferable first option.The HeadSmart initiative in the United Kingdom provides guidance to obtain brain imaging within 4 weeks of onset of persistent symptoms that are associated with CNS tumours. We advocate applying the same criteria in Canada in order to reduce delay in diagnosis of CNS tumours in children.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030132PMC
http://dx.doi.org/10.46747/cfp.6903165DOI Listing

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