Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1051/medsci/2023019 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Transcriptomic Analysis across Crayfish () Claw Regeneration Reveals Potential Stem Cell Sources for Cultivated Crustacean Meat.
Int J Mol Sci
August 2024
Centre for Bioinnovation, University of the Sunshine Coast (UniSC), 4 Locked Bag, Maroochydore, QLD 4558, Australia.
In the face of rising global demand and unsustainable production methods, cultivated crustacean meat (CCM) is proposed as an alternative means to produce delicious lobster, shrimp, and crab products. Cultivated meat requires starting stem cells that may vary in terms of potency and the propensity to proliferate or differentiate into myogenic (muscle-related) tissues. Recognizing that regenerating limbs are a non-lethal source of tissue and may harbor relevant stem cells, we selected those of the crayfish as our model.
View Article and Find Full Text PDFLong noncoding RNA plasmacytoma variant translocation 1 is overexpressed in cutaneous squamous cell carcinoma and exon 2 is critical for its oncogenicity.
Br J Dermatol
February 2024
Department of Medical Biochemistry and Microbiology (IMBIM).
Background: Cutaneous squamous cell carcinoma (cSCC) is one of the most common and fastest increasing forms of cancer worldwide with metastatic potential. Long noncoding RNAs (lncRNAs) are a group of RNA molecules with essential regulatory functions in both physiological and pathological processes.
Objectives: To investigate the function and mode of action of lncRNA plasmacytoma variant translocation 1 (PVT1) in cSCC.
A conditional RNA Pol II mono-promoter drives HIV-inducible, CRISPR-mediated cyclin T1 suppression and HIV inhibition.
Mol Ther Nucleic Acids
June 2023
Department of Immunology and Nanomedicine, Institute of Neuroimmune Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.
Gene editing using clustered regularly interspaced short palindromic repeats (CRISPR) targeted to HIV proviral DNA has shown excision of HIV from infected cells. However, CRISPR-based HIV excision is vulnerable to viral escape. Targeting cellular co-factors provides an attractive yet risky alternative to render viral escape irrelevant.
View Article and Find Full Text PDF[Cyclin B3: Locking female meiosis to await fertilization].
Med Sci (Paris)
March 2023
Équipe Mécanismes de la méiose, université Paris-Cité, CNRS, institut Jacques Monod, 75013 Paris, France.
Self-regulation of TNF-α Induces Dysfunction of Endothelial Colony-forming Cells from Patients with Venous Thromboembolic Disease.
Arch Med Res
November 2022
Unidad de Investigación Médica en Trombosis, Hemostasia y Aterogenesis, Instituto Mexicano del Seguro Social, Ciudad de México, Ciudad de México, México. Electronic address:
Background: Endothelial colony-forming cells (ECFCs) contribute to postnatal vasculogenesis. In venous thromboembolic disease (VTD), they are functionally abnormal and produce high concentrations of TNF-α.
Objective: To analyze the TNF-α signaling pathway and its relationship with the expression of cell-cycle regulators.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!