In the present study, we were interested in studying the amylolytic and antibacterial activity of some filamentous fungi isolated from the rhizosphere of cultivated plants in Tamanghasset region. Consequently, 11 pure strains belonging to the different fungal genera were isolated and . Positive result of amylolytic activity was revealed on all the isolated strains, with important hydrolysis zones of 54.33 ± 1.15 mm, 54.00 ± 3.61 mm, 52.00 ± 6.08 mm and 51.33 ± 15.01 mm for sp.1, sp., sp.2 and sp. respectively. In addition, analysis of variance () of the means of hydrolysis zones diameters shows that the values linked by the same letter do not show any significant difference at . Antibacterial activity of the isolated fungal was demonstrated by the agar cylinder technique against four pathogenic bacterial strains. The results showed a variability of the inhibition zones, thus the most important results were recorded against , and for all fungi which produced inhibition zones ranging from 15.33 ± 0.00 to 23.66 ± 1.71 mm. while all isolate had the lowest inhibition zone against . In conclusion, the obtained results indicated the isolated filamentous fungi have the potential to inhibit the four pathogenic bacterial strains, and , while simultaneously showed significant amylolytic activity.
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http://dx.doi.org/10.1016/j.heliyon.2023.e14350 | DOI Listing |
Mini Rev Med Chem
January 2025
Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, Johor Bahru 81310, Johor, Malaysia.
Indole, a ubiquitous structural motif in bioactive compounds, has played a pivotal role in drug discovery. Among indole derivatives, indole-3-carboxaldehyde (I3A) has emerged as a particularly promising scaffold for the development of therapeutic agents. This review delves into the recent advancements in the chemical modification of I3A and its derivatives, highlighting their potential applications in various therapeutic areas.
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October 2024
Supramolecular Compounds Division, Institute of General and Inorganic Chemistry, Uzbekistan Academy of Sciences, Tashkent, Uzbekistan.
The cocrystal (or supramolecular complex) between the Cu(II) complex of salicylic acid and uncoordinated piracetam has been synthesized. Its structure is characterized by elemental analysis, FT-IR, UV-Vis spectroscopy, and X-ray crystallography. Spectroscopic methods confirm the formation of the metal complex, while X-ray crystallography establishes the molecular and crystal structure of the obtained compound.
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January 2025
SRM Institute of Science and Technology: SRM Institute of Science and Technology (Deemed to be University), Department of Chemical Engineering, Kattankulathur, 603203, Chengalpattu, INDIA.
The rising threat of antimicrobial resistance among pathogens highlights the critical need for novel antimicrobial agents. This study explores the potential of natural products by investigating hexane extracts from the marine sponge Haliclona fibulata (HF) for their antibacterial efficacy. The well diffusion method of HF extract showed significant antibacterial activity against P.
View Article and Find Full Text PDFAdv Healthc Mater
January 2025
Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing, 100081, China.
Poor diabetic wound healing poses a critical threat to human health. Excessive oxidative stress and increased susceptibility to bacterial infection are key issues that impede diabetic wound healing. Cerium oxide nanoparticles (CeO NPs) have attracted increasing attention because of their unique antioxidant and antimicrobial properties.
View Article and Find Full Text PDFChem Biodivers
January 2025
Matrusri Education Society, Department of Sciences and Humanities, Matrusri Engineering College, Hyderabad, 500059, Hyderabad, INDIA.
In this work, we have adopted an easy route to synthesizing bis-1,2,3-triazole-based benzophenone compounds via a 1,3-dipolar cycloaddition reaction (Click Chemistry). All the target compounds achieved better yields though the microwave-assisted method than the conventional method. Target compounds structure were confirmed based on the IR, 1H NMR, 13C NMR and HR Mass analysis.
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