AI Article Synopsis
- Hyperparathyroidism-jaw tumour (HPT-JT) syndrome is an uncommon genetic disorder caused by a mutation in the CDC73 gene, affecting tumor suppression.
- This syndrome typically leads to a combination of dental tumors, parathyroid issues, and tumors in the kidneys and uterus.
- A case study presents a 30-year-old male diagnosed with HPT-JT syndrome, highlighting its impact and symptoms.
Article Abstract
Hyperparathyroidism-jaw tumour (HPT-JT) syndrome is a rare autosomal dominant disease. It is caused by a gene mutation of the tumour suppressor gene CDC73 that encodes for parafibromin. This syndrome predisposes to a triad occurrence of multiple maxillary or mandibular cemento-ossifying fibroma, parathyroid adenoma or carcinoma, and renal and uterine tumours. In this study, we report a case of HPT-JT occurring in a 30-year-old male patient.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017210 | PMC |
| http://dx.doi.org/10.1155/2023/4664619 | DOI Listing |
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