AI Article Synopsis
- The National Cancer Institute (NCI) has launched a program focused on developing new technologies for discovering drugs from natural products.
- A neural network-based bioinformatics platform has been created to analyze and visualize data from the NCI's 60 human tumor cell anticancer drug screen.
- This tool allows users to easily identify and group similar biological profiles based on chemical and taxonomic patterns, facilitating more efficient data analysis.
Article Abstract
National Cancer Institute (NCI) Program for Natural Product Discovery is a new initiative aimed at creating new technologies for natural product-based drug discovery. Here, we present the development of a neural network-based bioinformatics platform for visualization and analysis of natural product high-throughput screening data using the NCI's 60 human tumor cell anticancer drug screen. We demonstrate how the tool enables visualization of similar patterns of response that can be parsed both chemically and taxonomically, grouping NCI-60 biological profiles in one easy-to-use bioinformatics interface.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018511 | PMC |
| http://dx.doi.org/10.1021/acsomega.2c07416 | DOI Listing |
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