Comparison of ZOOMit-DWI sequence and conventional DWI sequence in endometrial cancer.

Zhong Nan Da Xue Xue Bao Yi Xue Ban

Department of Radiology, Second Xiangya Hospital, Central South University, Changsha 410011.

Published: January 2023

AI Article Synopsis

  • This study examines the effectiveness of using ZOOMit-DWI magnetic resonance imaging (MRI) compared to conventional SS-EPI DWI sequences for detecting small lesions in endometrial carcinoma.
  • It involved 37 patients diagnosed with endometrial carcinoma, where both imaging methods were evaluated for image quality and clinical value.
  • Results showed that ZOOMit-DWI had significantly better signal-to-noise and contrast-to-noise ratios, along with higher subjective scores for anatomical detail and lesion definition than SS-EPI DWI.

Article Abstract

Objectives: Magnetic resonance diffusion-weighted imaging (DWI) has important clinical value in diagnosis and curative effect evaluation on endometrial carcinoma. How to improve the detection rate of endometrial small lesions by DWI is the research focus of MRI technology. This study aims to analyze the image quality of small field MRI ZOOMit-DWI sequence and conventional single-shot echo-planar imaging (SS-EPI) DWI sequence in the scanning of endometrial carcinoma, and to explore the clinical value of ZOOMit-DWI sequence.

Methods: A total of 37 patients with endometrial carcinoma diagnosed by operation and pathology in the Second Xiangya Hospital of Central South University from July 2019 to May 2021 were collected. All patients were scanned with MRI ZOOMit-DWI sequence and SS-EPI DWI sequence before operation. Two radiologists subjectively evaluated the anatomical details, artifacts, geometric deformation and focus definition of the 2 groups of DWI images. At the same time, the signal intensity were measured and the signal-to-noise ratio (SNR), contrast to noise ratio (CNR), and apparent diffusion coefficient (ADC) of the 2 DWI sequences were calculated for objective evaluation. The differences of subjective score, objective score and ADC value of the 2 DWI sequences were analyzed.

Results: The SNR of the ZOOMit-DWI group was significantly higher than that of the SS-EPI DWI group (301.96±141.85 vs 94.66±41.26), and the CNR of the ZOOMit-DWI group was significantly higher than that of the SS-EPI DWI group (185.05±105.45 vs 57.91±31.54, P<0.05). There was no significant difference in noise standard deviation between the ZOOMit-DWI group and the SS-EPI DWI group (P>0.05). The subjective score of anatomical detail and focus definition in the ZOOMit-DWI group was significantly higher than that of the SS-EPI DWI group (both P<0.05). The subjective score of artifacts and geometric deformation of ZOOMit-DWI group was significantly lower than that of the SS-EPI DWI group (both P<0.05). ADC had no significant difference between the ZOOMit-DWI group and the SS-EPI DWI group (P>0.05).

Conclusions: The image quality of ZOOMit-DWI is significantly higher than that of conventional SS-EPI DWI. In the MRI DWI examination of endometrial carcinoma, ZOOMit-DWI can effectively reduce the geometric deformation and artifacts of the image, which is more conducive to clinical diagnosis and treatment.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10930561PMC
http://dx.doi.org/10.11817/j.issn.1672-7347.2023.220018DOI Listing

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