AI Article Synopsis
- Several cases of hemolytic disease of the fetus and newborn (HDFN) have been linked to warm-reacting immunoglobulin G (IgG) anti-M antibodies, but this report highlights two unique cases involving cold-reacting IgG anti-M.
- Both cases resulted in severe HDFN and led to the termination of pregnancies at 33 and 23 weeks due to fetal growth retardation.
- These instances are particularly notable as they represent the most severe cases of HDFN associated with cold-reacting IgG anti-M reported so far.
Article Abstract
Several cases of the hemolytic disease of the fetus and newborn (HDFN) caused by immunoglobulin G (IgG) anti-M antibodies have been reported, in which almost all the HDFN-associated anti-M were warmly reacting. Here we report two cases of severe HDFN associated with cold-reacting IgG anti-M. In both cases, pregnancy was terminated, in weeks 33 and 23 respectively, due to a diagnosis of fetal growth retardation (FGR). To our knowledge, these are the most severe HDFN cases caused by cold-reacting IgG anti-M.
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| http://dx.doi.org/10.22034/iji.2023.93993.2273 | DOI Listing |
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