Cellular therapies show promise for treatment of fibrosis. A recent article presents a strategy and proof-of-concept for delivering stimulated cells to degrade hepatic collagen in vivo. A discussion is presented surrounding the strengths of this approach and the potential to generalize this strategy of optimizing cell sources and activation stimuli to treat other types of fibrosis.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265036 | PMC |
http://dx.doi.org/10.1002/advs.202207396 | DOI Listing |
Adv Sci (Weinh)
June 2023
Department of Biomedical Engineering, School of Medicine, Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing, 100084, China.
Adv Sci (Weinh)
June 2023
Division of Plastic Surgery, Department of Surgery, Northwestern University-Feinberg School of Medicine, Chicago, IL, 60611, USA.
Cellular therapies show promise for treatment of fibrosis. A recent article presents a strategy and proof-of-concept for delivering stimulated cells to degrade hepatic collagen in vivo. A discussion is presented surrounding the strengths of this approach and the potential to generalize this strategy of optimizing cell sources and activation stimuli to treat other types of fibrosis.
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