Following Ervin Bauer we accept that a living system can be characterized by its stable nonequilibrium. We represent such a system by a model hierarchy and relate system stability to computational delays across the hierarchy. For natural computation across the system assembly we advocate chaotic computation, and evaluate computational delay at the different organizational levels of the hierarchy. We compute inter-elemental access speed for the atomic and cell levels, and conclude that cell-related speed is 1000-10,000 times that of the atom level, confirming that on moving from the system-as-itself level towards the system-as-atoms level overall level access speed reduces. We conclude that Bauer's living system description as a stable nonequilibrium is justified.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.biosystems.2023.104886 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The microcephaly-associated transcriptional regulator AUTS2 cooperates with Polycomb complex PRC2 to produce upper-layer neurons in mice.
EMBO J
January 2025
Department of Biochemistry and Cellular Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry (NCNP), Tokyo, 187-8502, Japan.
AUTS2 syndrome is characterized by intellectual disability and microcephaly, and is often associated with autism spectrum disorder, but the underlying mechanisms, particularly concerning microcephaly, remain incompletely understood. Here, we analyze mice mutated for the transcriptional regulator AUTS2, which recapitulate microcephaly. Their brains exhibit reduced division of intermediate progenitor cells (IPCs), leading to fewer neurons and decreased thickness in the upper-layer cortex.
View Article and Find Full Text PDFLong-lived entanglement of molecules in magic-wavelength optical tweezers.
Nature
January 2025
Department of Physics, Durham University, Durham, United Kingdom.
Realizing quantum control and entanglement of particles is crucial for advancing both quantum technologies and fundamental science. Substantial developments in this domain have been achieved in a variety of systems. In this context, ultracold polar molecules offer new and unique opportunities because of their more complex internal structure associated with vibration and rotation, coupled with the existence of long-range interactions.
View Article and Find Full Text PDFTargeting protein-ligand neosurfaces with a generalizable deep learning tool.
Nature
January 2025
Laboratory of Protein Design and Immunoengineering, Institute of Bioengineering, Ecole polytechnique fédérale de Lausanne, Lausanne, Switzerland.
Molecular recognition events between proteins drive biological processes in living systems. However, higher levels of mechanistic regulation have emerged, in which protein-protein interactions are conditioned to small molecules. Despite recent advances, computational tools for the design of new chemically induced protein interactions have remained a challenging task for the field.
View Article and Find Full Text PDFThe role of fluid friction in streamer formation and biofilm growth.
NPJ Biofilms Microbiomes
January 2025
FLOW, Department of Engineering Mechanics, KTH, Stockholm, Sweden.
Biofilms constitute one of the most common forms of living matter, playing an increasingly important role in technology, health, and ecology. While it is well established that biofilm growth and morphology are highly dependent on the external flow environment, the precise role of fluid friction has remained elusive. We grew Bacillus subtilis biofilms on flat surfaces of a channel in a laminar flow at wall shear stresses spanning one order of magnitude (τ = 0.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!