In this work we investigated the chemical constituents of water extract of the leaves of Cyclocarya paliurus. Two new megastigmane glycosides (3 and 8), three aliphatic alcohol glycosides (9-11), and two aromatic glycosides (12 and 13), along with fourteen known compounds were isolated, and their in vitro inhibitory activity against α-glucosidase was evaluated. Compounds 13 and 15-18 displayed inhibitory activity with IC values varying from 27.05 to 96.58 μM, and the structure-activity relationship among isolated compounds was discussed.
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| http://dx.doi.org/10.1016/j.fitote.2023.105473 | DOI Listing |
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