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Application of extracorporeal shockwave therapy to improve microcirculation in diabetic foot ulcers: A prospective study. | LitMetric

AI Article Synopsis

  • Extracorporeal shockwave therapy (ESWT) has potential benefits for wound healing by improving tissue microcirculation, especially in diabetic foot ulcer (DFU) patients.
  • A study involving 25 patients with type 2 diabetes and Wagner grade I to II DFUs showed that after 3 weeks of ESWT, tissue microcirculation significantly improved as measured by transcutaneous partial oxygen pressure (TcPO2).
  • Results indicated that the TcPO2 levels in the ESWT group reached a significant increase by the second week, suggesting that at least 6 sessions of ESWT over 2 weeks are necessary for noticeable improvement, and further research with larger samples is recommended.

Article Abstract

Extracorporeal shockwave therapy (ESWT) can induce wound healing by increasing tissue microcirculation. However, studies on the effect of ESWT on enhancing tissue microcirculation in diabetic foot ulcer (DFU), particularly on when the microcirculation increases after ESWT application, are still lacking. Therefore, we aimed to examine the effectiveness of ESWT in promoting microcirculation in DFU patients in a time-dependent manner. We included 50 feet of 25 patients with type 2 diabetes mellitus and Wagner grade I to II DFU in this study. The affected feet were used as the ESWT group and the unaffected contralateral feet were used as the control group. ESWT was performed in 3 sessions per week for a total of 3 weeks. Transcutaneous partial oxygen pressure (TcPO2) was used to evaluate the tissue microcirculation. The TcPO2 level (>43 mm Hg) in the ESWT group was recovered by the 2nd week of treatment, and statistical significance (P < .05) was demonstrated at the same time. From the 2nd week of ESWT, a significant increase in TcPO2 was observed in Wagner grade I and II DFU. These findings imply that the ESWT may improve microcirculation in patients with Wagner grades I to II DFU. However, this impact requires at least 2 weeks or more than 6 sessions. For better comparison, further studies with larger clinical groups and extended period are needed.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019234PMC
http://dx.doi.org/10.1097/MD.0000000000033310DOI Listing

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