The objective of this study was to examine the efficacy of a 5-week, tele-CO-OP intervention in children with organic acidemia. Thirty-four children were randomly divided into intervention and control groups. While 17 received the home program, 17 received the CO-OP Approach with telehealth twice a week along with the home program. Children were assessed through the Canadian Occupational Performance Measure, Pediatric Evaluation of Disability Inventory, Child and Adolescent Scale of Participation, Kid-KINDL Questionnaire, and Assistance to Participate Scale. Between-group analyses show significant benefits ( < .05) for the CO-OP group compared with the control group on the Performance and Satisfaction scales of the Canadian Occupational Performance Measure, and on the total scores of the Pediatric Evaluation of Disability Inventory, Child and Adolescent Scale of Participation, KINDL, and the Assistance to Participate Scale. The findings are preliminary results of benefits as this is the first trial, and the CO-OP approach applied through telerehabilitation had positive effects on children with organic acidemia.
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http://dx.doi.org/10.1177/15394492231156907 | DOI Listing |
JBMR Plus
February 2025
Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto 14040-901, Brazil.
Mineralizing cells release a special class of extracellular vesicles known as matrix vesicles (MV), crucial for bone mineralization. Following their release, MV anchor to the extracellular matrix (ECM), where their highly specialized enzymatic machinery facilitates the formation of seed mineral within the MV's lumen, subsequently releasing it onto the ECM. However, how MV propagate mineral onto the collagenous ECM remains unclear.
View Article and Find Full Text PDFPaediatr Perinat Epidemiol
January 2025
Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA.
Background: Epidemiologic studies have demonstrated that ambient concentrations of particulate matter < 2.5 μm (PM) are associated with reduced fecundability, the per cycle probability of conception. The specific constituents driving this association are unknown.
View Article and Find Full Text PDFActa Parasitol
January 2025
Department of Biomedicine and Biotechnology, Faculty of Medicine, University of Alcala, Alcala de Henares, Spain.
Purpose: Malaria remains a major global health challenge, particularly in sub-Saharan Africa and low- and middle-income countries (LMICs), contributing substantially to mortality and morbidity rates. In resource-limited settings, access to specialized diagnostic tests is often restricted, making basic blood analysis a valuable diagnostic tool. This study investigated the correlation between malaria infection and full blood count values in a rural region of Ghana during the 2022 rainy season, aiming to highlight diagnostic insights available from routine blood analyses.
View Article and Find Full Text PDFJ Pediatr Gastroenterol Nutr
January 2025
Hospices Civil de Lyon, Hôpital Femme Mère Enfant, Service de Gastroentérologie, Hépatologie et Nutrition Pédiatriques, Université Claude Bernard Lyon-1, CarMeN Laboratory, INRAE, UMR1397, INSERM, UMR1060, Pierre-Bénite, France.
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View Article and Find Full Text PDFNat Rev Gastroenterol Hepatol
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Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
In patients with disorders of gut-brain interaction (DGBI), overlapping non-gastrointestinal conditions such as fibromyalgia, headaches, gynaecological and urological conditions, sleep disturbances and fatigue are common, as is overlap among DGBI in different regions of the gastrointestinal tract. These overlaps strongly influence patient management and outcome. Shared pathophysiology could explain this scenario, but details are not fully understood.
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