AI Article Synopsis
- The study examined brain asymmetries in 442 healthy term-born neonates using advanced imaging techniques to understand their role in cognitive processes.
- Results showed that both structural and functional aspects of the neonatal cortex are significantly asymmetric.
- When comparing these findings to preterm neonates and healthy young adults, the research highlighted that while preterm birth and biological sex had minimal impact, there were notable differences between brain asymmetries in newborns and those in adults.
Article Abstract
Features of brain asymmetry have been implicated in a broad range of cognitive processes; however, their origins are still poorly understood. Here we investigated cortical asymmetries in 442 healthy term-born neonates using structural and functional magnetic resonance images from the Developing Human Connectome Project. Our results demonstrate that the neonatal cortex is markedly asymmetric in both structure and function. Cortical asymmetries observed in the term cohort were contextualized in two ways: by comparing them against cortical asymmetries observed in 103 preterm neonates scanned at term-equivalent age, and by comparing structural asymmetries against those observed in 1,110 healthy young adults from the Human Connectome Project. While associations with preterm birth and biological sex were minimal, significant differences exist between birth and adulthood.
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| http://dx.doi.org/10.1038/s41562-023-01542-8 | DOI Listing |
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