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Relationship between social support, functional outcomes and health-related quality of life in working-aged adults at three months after ischemic stroke: results from the FRAILTY study.
Health Qual Life Outcomes
January 2025
Department of Nursing, Faculty of Health Sciences, Palacký University, Olomouc, Czech Republic.
Background: The relationship between social support and functional outcomes and health-related quality of life (HRQoL) after ischemic stroke (IS) remains unclear, especially in working-aged patients.
Aim: To assess the relationship between perceived social support, functional outcomes, post-stroke psychosocial symptoms, and HRQoL in working-aged adults three months after IS.
Methods: A prospective and correlational design was used.
Association between pre-stroke frailty and post-discharge destination in acute stroke among Chinese older adults.
Top Stroke Rehabil
December 2024
Department of Nursing, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Aims: To investigate the association between pre-stroke frailty and discharge destination in hospitalized older adults in China.
Methods: We conducted this prospective cohort study in a tertiary care hospital in China. We enrolled patients aged 60 years and older admitted to the hospital for acute stroke from January 2022 to May 2022.
Frailty reduces penumbral volumes and attenuates treatment response in hyperacute ischemic stroke.
Age Ageing
November 2024
Department of Clinical Neurosciences, University of Cambridge, R3 Clinical Neurosciences (Box 83) Addenbrooke's Hospital Hills Road, Cambridge CB2 0QQ, UK.
Background: Frailty-the loss of physiological reserve to withstand a stressor event-is associated with poorer outcomes following acute stroke reperfusion therapies. However, the mechanisms underlying this relationship are poorly understood. This study investigated the association between frailty and penumbral volumes in hyperacute ischemic stroke.
View Article and Find Full Text PDF[Sarcopenia and Frailty in Stroke and Cardiovascular Disease].
No Shinkei Geka
November 2024
Division of Neurology, Department of Medicine, Jichi Medical University.
Sarcopenia is a progressive skeletal muscle disorder involving an accelerated loss of muscle mass and function. Frailty is characterized by a decline in the functioning of multiple physiological systems and an increased vulnerability to stressors. The incidence of these pathological conditions increases with age and is often accompanied by various acute or chronic disorders.
View Article and Find Full Text PDFPre-Stroke Frailty Negatively Affects Leptomeningeal Collateral Flow in Proximal Middle Cerebral Artery Occlusion.
Cerebrovasc Dis
November 2024
Department of Neurology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Introduction: The adequacy of blood flow from the leptomeningeal collaterals is considered one of the most important factors determining the rate of infarct progression and response to acute stroke treatments in the setting of large vessel occlusions. Several patient-related variables, including age, vascular risk factors, and laboratory parameters, have been proposed to explain the interindividual variability of collateral flow among stroke patients. This study aimed to assess how pre-stroke frailty, an aging-related syndrome characterized by a loss in the physiologic reserve of numerous body functions, affected the degree of leptomeningeal collateral flow in the setting of acute ischemic stroke.
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