We compared the passive permeability of cyclosporin A (CsA) derivatives with side chain deletions across lipid bilayers. CsA maintained passive permeability after losing any one of the side chains, which suggests that the propensity of the backbone of CsA is an important component for high passive permeability.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010161 | PMC |
| http://dx.doi.org/10.1039/d3ra01358h | DOI Listing |
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