Does environmental replication contribute to Bacillus anthracis spore persistence and infectivity in soil?

Res Microbiol

Department of Veterinary Pathobiology, Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA. Electronic address:

Published: June 2023

AI Article Synopsis

  • Bacillus anthracis is the bacteria that causes anthrax, primarily affecting herbivores that graze in areas contaminated with its spores.
  • There are differing views on whether these spores remain inactive in soil or if they can germinate and reproduce in that environment.
  • The review explores the significance of soil replication in the lifecycle of B. anthracis and its implications for disease spread.

Article Abstract

Bacillus anthracis is the zoonotic causal agent of anthrax. Its infectious form is the spore, which can persist in soil. Herbivores usually acquire the disease from grazing in spore-contaminated sites. There are two schools of thought regarding B. anthracis activities in soil. One contends the bacteria are obligate animal parasites and soil-based spores remain inert until taken up by another animal host. Others contend that spores can germinate in soil and the bacteria replicate and re-sporulate to maintain and/or increase spore numbers. This review discusses whether soil replication of B. anthracis is an important part of its life cycle.

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Source
http://dx.doi.org/10.1016/j.resmic.2023.104052DOI Listing

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