Short-term Side Effects of mRNA-based COVID-19 Vaccine Among Jordanian Population; a Cross-sectional Study.

Arch Acad Emerg Med

Department of Clinical Pharmacy and Therapeutics, Faculty of Pharmacy, Applied Science Private University, Amman, Jordan.

Published: February 2023

AI Article Synopsis

  • The study focuses on the side effects experienced by the Jordanian population after receiving mRNA-based COVID-19 vaccines, as approved by the FDA.
  • The research was conducted through a web-based survey among 533 participants, with data collected in August 2021, highlighting that about 56% reported side effects, mainly sore arms and fatigue.
  • Findings suggest that side effects were generally mild and self-limited, with certain demographics, like women and smokers, experiencing specific symptoms, aiming to reduce vaccine hesitancy.

Article Abstract

Introduction: One type of the developed COVID-19 vaccines that received emergency permission and was approved by the food and drug administration (FDA) is the mRNA-based vaccine. The aim of this study is to gather information on the Jordanian population's experience with the vaccine's side effects.

Methods: The study objectives were addressed through a cross-sectional study, which collected information regarding the short-term side effects experienced by the vaccinated individuals within one month following the injection of an mRNA-based COVID-19 vaccine. Data collection was carried out in August 2021. Participants were invited to take part in a self-administered web-based survey created using Google Forms.

Results: Among the study's participants (n= 533), about 56% experienced side effects after the first dose of the mRNA-based COVID-19 vaccine. The most commonly reported side effects after the first dose were sore arm at the injection site (91.6%), and fatigue (83.06%). The female gender was significantly associated with experiencing fatigue, discomfort, chills, and hair loss. Being over 30 years old was significantly associated with experiencing cough. Being a smoker was significantly associated with experiencing shortness of breath and gastrointestinal symptoms.

Conclusion: The mRNA-based COVID-19 vaccine side effects were common, yet, mild, local, and self-limited. The local pain at the injection site was the most commonly reported side effect. Hopefully, the study's findings will aid in lowering resistance to vaccination.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10008238PMC
http://dx.doi.org/10.22037/aaem.v11i1.1850DOI Listing

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