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| http://dx.doi.org/10.1038/s41598-023-29953-7 | DOI Listing |
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Reply - Letter to the Editor - "The genetically predicted causal associations between circulating 3-hydroxybutyrate levels and malignant neoplasms: A pan-cancer Mendelian randomization study".
Clin Nutr
January 2025
Department of Infectious Diseases, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China. Electronic address:
Comment on 'Systematic Druggable Genome-Wide Mendelian Randomization Identifies Therapeutic Targets for Sarcopenia' by Yin et al.-The Author's Reply.
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Department of Neurology, West China Hospital, Sichuan University, Chengdu, China.
Reply to 'The causal relationship between long-term exposure to ambient fine particulate matter and cognitive performance: Insights from Mendelian randomization'.
J Hazard Mater
October 2024
China Center for Health Development Studies, Peking University, Beijing 100191, China. Electronic address:
Li et al. [1] have commented on our recent paper investigating the association between exposure to fine particulate matter (PM) constituents and the risk of cognitive impairment [2]. They provided a Mendelian randomization (MR) analysis using large-scale genome-wide association study (GWAS) datasets from the European population, confirming a causal relationship between PM exposure and cognitive performance.
View Article and Find Full Text PDFIntegrated analysis of Mendelian Randomization and Bayesian colocalization reveals bidirectional causal association between inflammatory bowel disease and psoriasis.
Ann Med
November 2023
Department of Gastroenterology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China.
Article Synopsis
- Observational studies suggest a link between inflammatory bowel disease (IBD) and psoriasis, but the genetic and causal aspects of this relationship are not well understood.
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- * Eight candidate genetic variants and risk genes associated with the shared genetic basis of IBD and psoriasis were identified, which could help improve clinical strategies for treatment.*
Causal complexity in human research: On the shared challenges of behavior genetics, medical genetics, and environmentally oriented social science.
Behav Brain Sci
September 2023
Department of Psychology, University of Texas at Austin, Austin, TX,
We received 23 spirited commentaries on our target article from across the disciplines of philosophy, economics, evolutionary genetics, molecular biology, criminology, epidemiology, and law. We organize our reply around three overarching questions: (1) What is a cause? (2) How are randomized controlled trials (RCTs) and within-family genome-wide association studies (GWASs) alike and unalike? (3) Is behavior genetics a qualitatively different enterprise? Throughout our discussion of these questions, we advocate for the idea that behavior genetics shares many of the same pitfalls and promises as environmentally oriented research, medical genetics, and other arenas of the social and behavioral sciences.
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