AI Article Synopsis

  • The study aimed to compare phase analysis from positron emission tomography (PA) with magnetic resonance feature tracking (FT) for assessing left ventricular mechanical dyssynchrony in patients with ischemic heart disease.
  • Significant correlations were found between measures of dyssynchrony like histogram bandwidth and phase standard deviation from both techniques, particularly with global longitudinal strain and short axis circumferential strain.
  • The results highlighted a good overall agreement between the dyssynchrony indices derived from PET phase analysis and MR strain, indicating that both methods can effectively assess ventricular synchrony.

Article Abstract

Background: To compare phase analysis with positron emission tomography (PA) and magnetic resonance feature tracking derived myocardial strain (FT) for left ventricular (LV) mechanical dyssynchrony using PETMR system in patients with ischemic heart disease.

Methods And Results: Patients who underwent rest-pharmacological stress N ammonia PETMR were enrolled. Histogram bandwidth (BW) and phase standard deviation (PSD) were compared to global longitudinal, long axis radial, short axis circumferential, and radial strain (GLS, GRS, SA Circ, and SA Rad) obtained from FT. LV dyssynchrony index (SDI) derived from PA and FT were compared. BW and PSD showed significant correlations with FT (a Pearson's coefficient r = 0.64, P < .0001, and r = 0.51, P < .0001 for SA Circ; r = 0.67, P < .0001, and r = 0.74, P < .0001 for GLS; r = - 0.60, P < .0001, r = - 0.61, P < .0001 for SA Rad; r = - 0.62, P < .0001, and r = - 0.68, P < .0001 for GRS, respectively). Bland-Altman plots for SDI showed a preferable agreement (95% limit of agreement - 0.12 to 0.075, - 0.20 to 0.098, - 0.38 to 0.077, and - 0.37 to 0.032; bias 0.0068 ± 0.056, 0.026 ± 0.068, 0.11 ± 0.088, and 0.13 ± 0.079 for SA Circ, SA Rad, GLS, and GRS, respectively).

Conclusion: In simultaneous acquisition using PETMR, comparison of PET phase analysis and MR strain showed a good correlation.

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Source
http://dx.doi.org/10.1007/s12350-023-03225-3DOI Listing

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