Contemporary management of epilepsy in pregnancy.

Curr Opin Obstet Gynecol

Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Stanford University, Stanford, California, USA.

Published: April 2023

AI Article Synopsis

  • The prevalence of epilepsy during pregnancy is rising in the U.S., with more individuals using newer antiseizure medications.
  • Recent research focuses on preconception counseling, contraceptive practices, and the management of antiseizure medications throughout pregnancy.
  • Although newer medications may reduce risks for fetal and maternal outcomes, there is still an increased risk of severe maternal morbidity and hospital readmission, highlighting the need for careful monitoring during pregnancy.

Article Abstract

Purpose Of Review: The number of reproductive aged people with epilepsy in the United States is increasing, making epilepsy during pregnancy more prevalent. Simultaneously, more people are using newer generations of antiseizure medications before, during and after pregnancy. Here, we review current evidence on contemporary management and outcomes of pregnancies among people with epilepsy.

Recent Findings: This review evaluates recent literature to summarize current practices in preconception counselling, contraception, antiseizure medications before, during and after pregnancy, and peri-partum and postpartum risks in people with epilepsy.

Summary: With the introduction of newer generation antiseizure medications being used during pregnancy, current literature shows that there may be decreased risk in adverse foetal and maternal outcomes. In the peri-partum and postpartum period, recent literature shows that people with epilepsy have an increased risk of severe maternal morbidity and hospital readmission. Given this, as well as considerations for dosing of antiseizure medications, close surveillance of people with epilepsy during pregnancy is warranted.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023363PMC
http://dx.doi.org/10.1097/GCO.0000000000000844DOI Listing

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